• Efficient treatment of infertility due to sperm DNA damage by ICSI with testicular spermatozpna.
    Human Reproduction Vol.20, No.1pp.48, 226-230, 2005
  • Comparison of the survival of human biopsied embryos after cryopreservation with for different methods using non-transfarable embryos.
    Human Reproduction Vol.20,a No.6pp.1615-1618, 2005
  • High magnitude of light retardation by the zona pellucida is associated with conception cycles.
    Hum Reprod. 2005 Jun;20(6):1596-606.
  • Occurrence and development consequences of vacuoles thoughout preimplantation devwlopment Fertility and Sterility vol.83,No.6,June 2005
  • Observational clinical follow-up of oocyte cryopreservation using a slow-freezing method with 1,2-Propanediol plus sucrose followed by ICSI
    Human Reproduction Vol.20,No.7.pp.1975-1980,2005
  • Frequency of aneuploidy in sperm from patients with extremely severe male factor infertility.
    Human Reproduction Vol.20,No.8 pp.2140-2152,2005
  • Promising results with 306 single blastocyst transfers.
    Anueploid analysis of tripronuclear zygotes derived from in vitro fertilization and intracytoplasmic sperm injection in humans Fertility and Sterility Vol.83, No.6, June 2005
  • Cryoloop vitrification of rabbit oocytes
    Human Reproduction Vol.20,No.7 pp.1969-1974,2005
  • Treatment option for sperm- or oocyte- related fertilization failure: assisted oocyte activation following diagnostic heterologous ICSI.
    Hum Reprod. 2005 Aug;20(8):2237-41.
  • Early pronuclear breakdown is a good indicator of embryo quality and viability
    Fertility and Sterility Vol.85, No.4, October 2005
  • The use of the modified hypo-osmotic swelling test for the selection of immotile testicular spermatozoa in patients treated with ICSI : a randomized controlled study
    Human reproduction 2005
  • Relationship between pre-embryo pronuclear morphology (zygote score) and standard day 2 or 3 embryo morphology with regard to assisted reproductive technique outcomes.
    Fertil Steril. 2005 Oct;84(4):900-9.
  • Use of both earrly cleavage and day2 mononucleation to predict embryos with high implantatioon potential in intracytoplasmic sperm injection cycles
    Fertil Steril. 2005 Nov;84(5):1411-1415.
  • Comparision of pronuclear zygote morphology and early cleavage status of zygote as additional criteria in the selection of day3 embyos: a randomized study
    Fertility and Sterility, vol.85, No.2, Feb, 2006
    Day3胚選択時における付加的基準としての前核形態とearly cleavage の比較~無作為検討~
  • Removal of lysed blastomerea from frozen-thawed embryos improbes implantation and pregnancy rates in frozen embyo transfer cycles
    Fertility and Sterility, vol.84, No.6, Dec, 2005
  • Fluorescence in situ hybridization reanalysis of day-6 human blastocysts diagnosed with aneuploidy on day3
    Fertility and Sterility, vol.84, No.5, Nov, 2005
  • Value of the sperm deoxyribonucleic acid fragmentation level, as measured by the sperm chromatin dispersion test, in the outcome of in vitro fertilization and intracytoplasmic sperm injection
    Fertillity and Sterility Vol.85,N0.2, February 2006.
  • Pregnancies and live births after trophectoderm biopsy and preimplantation genetic testing of human blastocysts
  • Confocal microscopic analysis of the spindle and chromosome configurations of human oocytes matured in vitro
    Fertillity and Sterility Vol.85,N0.4, April 2006.
  • Randomized comparison of two different blastocyst grading systems
    Fertillity and Sterility  VOL.85, NO.3, March 2006
  • Title:The use of recombinant LH (lutropin alfa) in the late stimulation phase of assisted reproduction cycles: double blind, randomized, prospective study
    Human Reproduction Vol.21, No.1 pp90-94, 2006
  • Title:Urinary follicle-stimulating hormone (FSH) in more effective than recombinant FSH in older women in a controlled randamized study
    Fertility and Sterility Vol.85, No.5, May 2006
  • Title:Towards defining parameters for a successful single embryo transfer in frozen cycles
    Human Reproduction Vol.21, No.5 pp.1179- 1183, 2006
  • Mitochondrial content reflects oocyte variability and fertilization outcome.
    Fertil Steril. 2006 Mar;85(3):584-91.
  • Aseptic vitrification of human germinal vesicle oocytes using dimethyl sulfoxide as a cryoprotectant
    Fertility and Sterility Vol.85, No.3, March 2006
    凍結保護剤としてdimethyl sulfoxide (DMSO)を用いたヒトGV卵の無菌的凍結保存
  • Use of a medium buffered with N-hydroxyethylpiperazine-N-ethanesulfonate(HEPES)
    introcytoplasmic sperm injection procedures is detrimental to the outcome of in vitro fertilization.
    Fertility and sterility Vol.85,No.5,2006
  • ICSI outcomes in obstructive azoospremia:influence of the origin of surgically retrieved spermatozoa and the cause of obstruction
    Human Reproduction vol.21,No4pp.1018
  • Morphological scoring of human pronuclear zygotes for prediction of pregnancy outcome
    Human Reproduction October 2005
  • Randomized single versus double embryo transfer: obstetric and paediatric outcome
    and a cost-effectiveness analysis
    Human Reproduction October Vol.21, No.1, 2006
  • Role of total antioxidant capacity in the differential growth of human embryos in vitro
    Fertility and Sterility Vol.86,No.2,August 2006,Canada
  • Cryopreserved embryo transfers suggest that endmetrical receptivity may contribute to reduced success rates of later developing embryo
    Fertility and Sterility Vol.86 No4, October.2006
  • Nuclear and cytoplasmic maturation of in vitro matured human oocytes after temporary nuclear arrest by phosphodiesterase 3-inhibitor
    Human Reproduction Vol.22, No.5 pp. 1239-1246, 2007
  • Limited value of morphological assessment at days 1 and 2 to predict blastocyst development potential:A prospective study based on 4042 embryos
    Human Reproduction Vol.22,No.7 pp. 1978- 1981,2007
  • Oocyte euploidy, pronuclear zygote morphology and embryo chromosomal complement
    Human Reproduction Vol.22, No.1 pp. 241-249
  • Variable aneuploidy mechanisms in embryos from couples with poor reproductive histories undergoing preimplantation genetic screening.
    Hum Reprod. 2007 Jul;22(7):1844-53. 2007
  • Morphologic parameters of early cleavage-stage embryos that correlate with fetal development and delivery : prospective and applied data for increased pregnancy rates
    Human Reproduction Vol. 22, No. 1 pp230-240, 2007
  • Metabolism of human embryos following cryopreservation : Implications for the safety and selection of embryos for transfer in clinical IVF
    Human Reproduction Vol.22, No.3 pp. 829-835, 2007
  • Exposure to human chorionic gonadotropin during in vitro maturation does not improve the maturation rate and developmental potential of immature oocytes from patients with polycystic ovary syndrome
    Fertility and Sterility Vol.89, No. 1, January 2008
  • Osmotic responses and tolerance limits to changes in external osmolalities, and oolemma permeability characteristics, of human in vitro matured MⅡ oocytes
    Human Reproduction Vol.22, No.7 pp.1959-1972, 2007
  • Contrasting patterns in in vitro fertilization pregnancy rates among fresh autologous , fresh oocyte donor , and cryopresevrved cycles with the use of day 5 or day6 blastocysts may reflect differences in embryo-endometrium synchrony
    Fertility and Sterility Vol.89,No.1 January 2008
  • Is fine morphology of the human sperm nuclei affected by in vitro incubation at 37℃?
    Fertility and Sterility Vol.88,No.6,December 2007
  • The relative contribution of assisted reproductive technologies and ovulation induction to multiple births in the United States 5 years after the Society for Assisted Reproductive Technology/American Societyfor Reproductive Medicine recommendation to limit the number of embryos transferred.
    Fertility and Sterility Vol.88,No.6,December 2007
  • Early cleavage does not predict treatment outcome following the use of GnRH antagonists in women older than 35
    FERTIRRITY AND STERILITY VOL.88, NO.6, December 2007
  • Alterd composition of the cumulus-oocyte complex matrix during in vitro maturation of oocytes
    Human Reproduction Vol. 22, No. 11 pp. 2842-2850, 2007
  • Day-3 embryo morphology predicts euploidy among older subjects
    Fertility and Sterility Vol.89, No.1, January 2008
  • Permeability of human oocytes to and their survival and spindle configurations after slow cooling cryopresevation
    Human Reproduction Vol.22,No.10 pp.2776-2783,2007
  • Differences in ovarian function parameters between Chinese and Caucasian oocyte donors: do they offer an explanation for lower IVF pregnancy rates in Chinese women?
    Human Reproduction Vol.22,No.11 pp.2879-2882,2007
  • Oxygen concentration during mouse oocyte in vitro maturation affects embryo and fetal development.
    Human Reproduction Vol.22,No.10 pp2764-2775 2007
  • Adequate ovarian follicular status does not prevent the decrease in pregnancy rates associated with high sperm DNA fragmentation
  • Isolated teratozoospermia dose not affect in vitro fertilization outcome and is not an indication for intracytoplasmic sperm injection
    Fertility and Sterility Vol.88, No.6, December 2007
  • Live birth rates after tranfer of equal number of blastocysts or cleavage- stage embryo in IVF.. A systematic review and meta-analysis
    Human Reproduction Vol.23,No.1pp.91-99,2008
  • Human blastocyst morphological quality is significantly improved in embryos classified as fast on day 3(≧10cells ), bringing into question current embryological dogma
    Fertility and Sterility Vol.89,No.2 2008
  • Failed fertilization after ICSI and spermiogenic defects
    Fertility and Sterility Vol.89,No.4,April 2008
  • Randomized double-blind comparison of laser zona pellucida thinning and breaching in frozen-thawed embryo transfer at the cleavage stage.
    Fertility Sterility Vol.89,No5,May 2008
  • Do sperm DNA integrity tests predict pregnancy with in vitro fertilization?
    Fertility Sterility Vol.89,No4,April 2008
  • Predictors of ongoing pregnancy after single-embryo transfer following mild ovarian stimulation for IVF
    Fertility and Sterility Vol.89, No.5, May 2008
  • Day 4 versus day3 embryo transfer:a prospective study of clinical outcomes
    Fertility and Sterility Vol. 89, No. 3, March 2008
  • Genetic screening in 2,710 infertile candidate couples for assisted reproductive techniques : results of application of Italian guidelines for the appropriate use of genetic tests
    Fertility and Sterility Vol.89 No.4 April 2008
  • Diagnostic efficiency, embryonic development and clinical outcome after the biopsy of one or two blastomeres for preimplantation genetic diagnosis.
    Hum Reprod. 2008 Mar;23(3):493-8.
  • Integrity rate of pronuclei after cryopreservation of pronuclear-zygotes as a criteria for subsequent embryo development and pregnancy
    Human Reproduction Vol.23, No.4, pp.819-826, 2008
  • Vitrification of preimplantation genetically diagnosed human blastocysts and its contribution to the cumulative ongoing pregnancy rate per cycle by using a closed device
    Fertility and Sterrility Vol.89, No.4, April 2008
  • Day4 embryo selection is epual to Day5 using a new embryo scoring system validated in single embryo transfers
    Human Reproduction Vol.23, No.7, pp.1505-1510, 2008
  • Human immature oocytes grow during culuture for IVM
    Human Reproduction Vol.23, No.1, pp.37-45, 2008
  • Autologous mature follicular fluid:its role in in vitro maturation of human cumulus-removed oocytes
    Fertility and Sterility Vol.90, No.4, October 2008
  • The impact of spermatozoa preincubation time and spontaneous acrosome reaction in intracytoplasmic sperm injection: a controlled randomized study
    Fertility and Sterility Vol.90, No.3, September 2008
  • Severe cytoplasmic abnormalities of the oocyte decrease cryosurvival and subsequent embryonic development of cryopreserved embryos
    Human Reproduction Vol.23, No.8, pp.1778-1785, 2008
  • A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification:vitrification is associated with higher survival, metabolism and blastocyst formation
    Human Reproduction Vol.23, No.9 pp. 1976-1982, 2008
  • Impact of early cleaved zygote morphology on embryo development and in vitro fertilization-embryo transfer outcome: a prospective study
    Fertility and Sterility Vol.89,No.6 June 2008
  • Metabolic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection
    Human Reproduction 2008, Vol.23,No.7
  • Role of coculture in human in vitro fertilization: a meta-analysis
    Fertility and Sterility 2008, Vol.90,No.4, October
  • Cryopreservation of human embryos by vitrification or slow freezing: a systematic review and meta-analysis
    Fertility and Sterility 2008, Vol.90,No.1,July
  • Effect of hyaluronan-enriched transfer medium on implantation and prednancy rates after day3 and day5 embryo transfers:a prospective randomized study
    Fertility and sterility vol. 90 No3 September 2008
  • How viable are zygotes in which the PN are still intact at 25 hours?
    Fertility and Sterility Vol.90, No.3, September 2008
  • Freezing within 2h from oocyte retrieval increases the efficiency of human oocyte cryopreservation when using a slow freezing/rapid thawing protocol with high sucrose concentration
    Human Reproduction 2008, Vol.23, No.8
  • Sperm head`s birefringence : a new criterion for sperm selection
    Fertility and Sterility Vol.90, No.1, July 2008
  • Quantitative morphometrical characterization of human pronuclear zygotes
    Human Reproduction Vol.23, No.9 pp.1983-1992, 2008
  • Dopamine agonist administration causes a reduction in endometrial implants through modulation of angiogenesis in experimenrally induced endometrisis
    Human Reproduction; 24: 1025-, 2009
  • Choosing a culture medium: making informed choices
    Fertility and Sterility Vol. 90, No. 3, 2008
  • Permature ovarian failure and dehydroepiandrosterone
    FERTIRRITY AND STERILITY VOL.91, NO.2, February 2009
  • Location of endometrial polyp and pregnancy rate in infertility patients
  • The plausibility of Helicobacter pylori-related infertility in Japan
    FERTIRRITY AND STERILITY VOL.90, NO.3, September 2008
  • Spindle imaging: a marker for embryo development and implantation
  • Comparative protein-profile analysis of implanted versus non-implanted human blastocysts
    Human Reproduction Vol.23, No.9, 2008
  • Soy food and isoflavone intake in relation to semen quality parameters among men from an infertility clinic
    Human Reproduction Vol.23,No.11 pp.2584-2590,2008
  • Food intake and its relationship with semen quality:a case-control study
    Fertility and Sterility Vol.91,No.3,March 2009
  • Acetaldehyde differentially affects the growth of uterine leiomyomata and myometrial cells in tissue cultures
    Fertility and Sterility Vol.91,No.2,February 2009
    アセトアルデヒド(アルコールの代謝物)」はin vitroで子宮筋腫や子宮筋の発育に影響する
  • Impact of day3 or day5 embryo transfer on pregnancy rates and multiple gestations
    Fertility and Sterility Vol.91,No.5,May 2009
  • Myo-inositol may improve oocyte quality in intracytoplasmic sperm injection cycles.
    Fertility and Sterility Vol.91,No.2,February 2009
  • Coiled sperm from infertile patients:characteristics,associated factors and biological implication
    Human Reproduction Vol.24,No.6 pp.1288-1295,2009
  • Single Day 2 embryo versus blastocyst-stage transfer: a prospective study integrating fresh and frozen embryo transfers
    Human Reproduction Vol.24,No.5,2009
  • In vitro culture under physiologic oxygen concentration improves blastocyst yield and quality: a prospective randomized survey on sibling oocytes
    Fertility and Sterility Vol.91,No.4,April 2009
  • Correlation between DNA damage and sperm parameters: a prospective study of 1633 patients
    Fertility and Sterility Vol.91,No.5,May 2009
  • Long-term liquid nitrogen vapor storage of mouse embryos cryopreserved using vitrification or slow cooling
    Fertility and Sterility Vol.91,No.5, May 2009
  • Asian ethnicity is associated with reduced pregnancy outcomes after assisted reproductive technology
    Fertility and Sterility Vol.87,No.2,February 2007
  • Does ethnicity influence in vitro fretilization(IVF) birth outcomes?
    Fertility and Sterility Vol.91,No.6,June 2009
  • DrIncrease in scrotal tempereture in car drives
    Human Reproduction, Vol. 15, No.6, 2000
  • Increase in scrotal temperature in laptop computer users
    Human Reproduction, Vol. 20, No.2 ,2005
  • Influence of the type of undertrousers and physical activity on scrotal temperature
    Human Reproduction, Vol. 20, No.4, 2005
  • DNA damage and metabolic activity in the preimplantation embryo
    Human Reproduction, Vol. 24, No.1 pp81-91, 2009
  • Effect of triploidy after intracytoplasmic sperm injection on in vitro fertilization cycle outcome
    Fertility and Sterility Vol.91 No.1, January 2009
  • Electrical activation of oocytes after intracytoplasmic injection:a controlled ramdomized study
    Fertility and Sterility Vol.91 No.1, January 2009
  • A controlled randomaized trial evaluating the effect of lowered incubator oxygen tention on live births in a predominantly blastocyst transfer program
    Human Reproduction, Vol. 24, No.2 ,2009
  • valiation of a disposable plastic Neubauer counting chamber for semen analysis
    Fertility and Sterility Vol.91 No., February 2009
  • Viability and function of the cryopreserved whole ovary: in vitro studies in the sheep
    Human Reproduction,Vol.27,No.7 pp.1684-1694,2009
  • Emotional distress of infertile women in japan
    Human Reproduction,Vol.16,No.5 ,2001
  • A prospective study of psychosocial stress and fertility in women
    Human Reproduction,Vol.12,No.10 ,1997
  • A prospective study of stress among women undergoing in vitro fertilization or gamete intrafallopian transfer
    Fertility and Sterility Vol.76 No.4, October 2001
  • The effect of selecting oocytes for insemination and transferring all resultant embryos without selection on outcomes of assisted reproduction
    Fertility and Sterility Vol.91 No.1, January 2009
  • The value of blastocoele re-expantion in the selection of a viable thawed blastocyst for transfer
    Fertility and Sterility Vol.91 No.2, February 2009
  • Bacterial endotoxin(LPS)-induced DNA damege in preimplanting embryonic and uterine cells inhibits implantation
    Fertility and Sterility Vol.91 No.5, May 2009
  • L-Carnitine decreases DNA damage and improves the in vitro blastocyst development rate in mouse embryos
    Fertility and Sterility Vol.91 No.2, February 2009
  • New media for culture to blastocyst
    Fertility and Sterility Vol.91 No.3, March 2009
  • Laser zona thinning in women aged ≦37 years: a randomized study
    Fertility and Sterility Vol.91 No.4, April 2009
  • Viable pregnancies can occur after 24-hour incubation of ejaculated sperm before intracytoplasmic sperm injection
    Fertility and Sterility Vol.91 No.4, April 2009
  • Optimizing the number of blastocyst stage embryos to transfer on day 5 or 6 in women 38 years of age and older: a Society for Assisted Reproductive Technology database study
    Fertility and Sterility Vol.91 No.1, January 2009
  • Semen preparation methods and apotosis:swim-up versus gradient-density centrifugation technique
    Fertility & Stelitity Vol.91, no. 2, February 2009
    精子分離方法と精子アポトーシス;swim up vs. 密度勾配遠心法
  • A hgih oocyte yield for intracytoplasmic sperm injection treatment is associated with an increased chromosome error rate
    Fertility & Stelitity Vol.91, no. 3, March 2009
  • Nuclear maturation and structural components of nonhuman primate cumulus-oocyte complexs during in vivo and in vitro maturation
    Fertility & Sterility Vol. 91, No. 5, May 2009
  • Assessment of a new in vitro maturation system for mouse and human cumulus-enclosed oocytes: three-dimansional prematuration culture in the presence of a phosphdiesterase 3-inhibitor
    Human Reproduction Vol.24, No.8
  • Evoluation of two incubation emvironments-ISO class 8 v.s. ISO class 5-on ICSI cycle outcome
    Fertility and Sterility,VOL.91, NO.5, 2009
  • Nitric oxide metabolite production in the human preimplantation embryo and successful blastocyst foemation
    Fertility and Sterility,VOL.91, NO.4, 2009
  • Is there a limit for the number of in vitro fertilization cycles for an individual patient?
    Fertility and Sterility,VOL.91, NO.4, 2009
  • Modelling the impact of single embryo transfer in a national health service IVF programe
    Human Reproduction, VOL.24, NO.1, 2009
  • Meiotic spindle dynamics in human oocytes following slow-cooling cryopreservation
    Human Reproduction, VOL.9, NO.9, 2009
  • Blastocyst transfer dose not cause a sex-ratio imbalance
    Fertility and Sterility,VOL.92, NO.4, 2009
  • Infertility knowledge and attitudes in urban high school students
    Fertility and Sterility,VOL.90, NO.6, 2009
  • Risk of contamination of germplasm during cryopreservation and cryobanking in IVF units
  • IVFにおける凍結保存による生殖質の汚染の危険性
    Human Reproduction, VOL.24, NO.10, 2009
    Fresh testicular sperm retrieved from men with spinal cord injury retains equal fecundity to that from men with obstructive azoospermia via intracytoplasmic spem injection
    Fertility and Sterility Vol. 92, No. 4
  • Artificial oocyte activation with calcium ionophore A23187 in intracytoplasmic sperm injection cycles using surgically retrieved spermatozoa.
    Fertility & Stelitity Vol.92, no. 1, July 2009
  • Neonatal outcome after vitrified day3 embryo transfers: a preliminary study
    Fertility & Stelitity Vol.92, no. 1, July 2009
  • Embryo cryopreservation in the presence of low concentration of vitrification solution with sealed pulled straws in liquid nitrogen slush
    Human Reproduction, vol.24 No.4 pp.797-804.2009
    sealed pulled strawsを用いた低濃度ガラス化液における液体窒素slushでの胚凍結保存
  • Disrupted gene pattern in patients with repeated in vitro fertilization(IVF) failure.
    Hum Reprod,Vol.24. No.10, 2009
  • An in vivo cluture system for human embryos using an encapsulation technology:a pilot study.
    Hum Reprod,Vol.24. No.4, 2009
  • The DNA integrity of cryopreserved spermatozoa separated for use in assisted reproductive technology is unaffected by the type of cryoprotectant used but is related to the DNA integrity of the fresh separated preparation
    Fertility and Sterility Vol.92,No.3,September 2009
  • Selection of sperm based on combined density gradient and Zeta method may improve ICSI outcome
    Human Reproduction, VOL.24, NO.10, 2009
  • Low-oxygen compared with high-oxygen atmosphere in blastocyst culture, a prospctive randomized study
    Fertility and Sterility Vol.91,No.6, 2009
  • Comparison of survival and embryonic development in human oocytes cryopreserved by slow-freezing and vitrification
    Fertility and Sterility Vol.92,No.4, 2009
  • Live birth sex rations are not influenced by blastocyst-stage embryo transfer.
    Fertility and Sterility Vol.92,No.3,September 2009
  • Meiotic spindle recovery is faster in vitrification of numan oocytes compared to slow freezing.
    Fertility and Sterility Vol.91,No.6,June 2009
  • At what age can human oocytes be obtained?
    Fertility and Sterility Vol.92,No.2, 2009
  • Activated caspases in thawed epididymal and testicular spermatozoa of patients with congenital bilateral absence of the vas deferens and intracytoplasmic sperm injection outcome
    Fertility and Sterility Vol.92,No.2,2009
  • Oocyte activation ability correlates with head flatness and presence of perinuclar theca substance in human and mouse sperm
    Human Reproduction Vol.24, No.10, 2009
  • Fertilization and pregnancy using cryopreserved testicular sperm for intracytoplasmic sperm injection with azoospermia
    Fertility Sterility Vol.92 No.1 July 2009
  • Selective microsurgical removal of a pronucleus from tripronucler human oocyte to restore diploidy:disregard but valuable?
    Frtility Sterility Vol.92 No.3 September 2009
  • Vtrification of immature mouse oocyte using stepwise equilibration before or after in vitro maturation
    Fertikity & Stelitity Vol 92,no.3, September 2009
  • Assesment of the developmental competence of human somatic cell nuclear transfer embryos by oocyte morphology classification
    Fertikity & Stelitity Vol 91,no.6, 2009
  • Children born after cryopreservation of embryos or oocytes: a systematic review of outcome data
    Human Reproduction Vol.24, No.9, 2009
  • Assessment of day-3 morphology and euploidy for individual chromosomes in embryo that develop to the blastocyst stage
    Fertikity & Stelitity Vol 91,no.6, 2009
  • Comparison of development and implantation of human embryos biopsied with two different methods: aspiration and Displacement
    Fertikity & Stelitity Vol 92,no.2, 2009
  • Preimplantation aneuploid embryos undergo self-correction in correlation with their developmental potential
    FERTIRRITY AND STERILITY VOL.92, NO.3, September 2009
  • Rhesus macaque embryos derived from MⅠ oocytes maturing after retrieval display high rates of chromosomal anomalies
    Human Reproduction, VOL.24, NO.4, 2009
  • Is there an advantage in scoring early embryos on more than one day?
    Human Reproduction, Vol.24, No.9 pp. 2104-2113, 2009
  • Sperm head morphology is related to high deoxyribonucleic acid stainability assessed by sperm chromatin structure assay
  • Evaluation of human sperm function after being cryopreserved within the zona pellucid
  • Reduction of multiple pregnancy rate in a preimplantation genetic diagnosis programme after introduction of single blastocyst transfer and cryopreservation of blastocysts biopsied on day3
  • Cumulus cells and their extracellular matrix affect the quality of the spermatozoa penetrating the cumulus mass
  • A randomized controlled study of human serum albumin and serum substitute supplement as protein supplements for IVF culture and the effect on live birth rates
  • Location of herniation predicts implantation behaviour of hatching blastocysts.Thomas EBNER, Irmhild GRUBER, Marianne MOSER Austria accepted 2007
  • Preimplantation factor:non-invasive biomarker for embryo selection for in vitro fertilization
  • Vitrification of isolated human blastomeres
    Fertility and Sterility Vol.93,No.2,Junuary,2010 Spain
  • Embrtonic origin of preimplantation factor(PIF): biological activity and partial characterization‐European Society for Human Reproduction and Embryology 1996 from USA
  • Mechanics of human blastocyst hatching in vitroDr Henry SathananthanReproductive BioMedicine Online 2003  Australia
  • Automatic user-independent zona pellucida imaging at the oocyte stage allows for the prediction of preimplantation development
    Thomas Ebner, Ph.D.,et. al., Fertility and Sterility 2009, Austria
  • Birefringence characteristics in sperm heads allow for the selection of reacted spermatozoa for intracytoplasmic sperm injection
    Luca Gianaroli, M.D. et al Italy
    FERTIRRITY AND STERILITY VOL.93, NO.3, February 2010
  • Sperm DNA fragmentation :mechanismes of origin, impact on reproductive outcome, and analysisDenny Sakkas, Ph.D. et al Massachusetts
  • Beneficicial effect of autologous endometrial cell coculture in patients with repeat implantation failure.
  • Effect of vitrification and beta-mercaptoethanol on reactive oxygen species activity and in vitro development of oocytes vitrified before or after in vitro fertilization.
  • DNA fragmentation of normal spermatozoa negatively impacts embryo quality and intracytoplasmic sperm injection outcome.
  • Analysis of spindle characteristics and embryo quality in mice stimulated with letrozole using Polscope image.
  • Impact of oocyte cryopreservation on embryo development.
  • Thyroid hormone supplementation improves bovine embryo development in vitro.
  • Embryo quality and implantation rate in two different culture media: ISM1 versus Universal IVF Medium
    「培地による胚の質と着床率の検討(ISM1 vs Universal IVF Medium)」
  • Morphologic indicators predict the stage of chromatin condensation of human germinal vesicle oocytes recovered from stimulated cycles
  • Embryo development of fresh versus vitrified metaphase Ⅱ oocytes after ICSI : a prospective randamized sibling oocyte study
  • A prospective, randomized trial on the effect of atmospheric versus reduced oxygen concentration on the outcome of intracytoplasmic sperm injection cycles
    ICSIサイクルにおける大気 vs 低酸素の影響~前方視的無作為化試験~
  • Does severe teratozoospermia affect blastocyst formation, live birth rate and other clinical outcome parameters in ICSI cycles?
    B.et al. Fertil Steril.2010 USA
  • Effect of air quality on assisted human reproduction
    Human Reproduction 2010 USA
  • Comparison of 5% and ambient oxygen during days 3-5 of in vitro culture of human embryos
    「Day3-5間での異なる酸素分圧による体外培養の比較(5% vs 外気酸素分圧)」
  • Noninvasive metabolomic profiling as an adjunct to morphology for noninvasive embryo assessment in women undergoing single embryo transfer.
  • A new culuture technique that allows in vitro meiotic prophase development of fetal human oocytes.
    Human Reprocuction,Vol.25,No.1pp.74-84 2010 Spain
  • Clinical significance of sperm DNA damage in assisted reproduction outcome.
    Human Reprocuction,Vol.25,No.7pp.1594-16088 2010 UK
  • Injection of day 2 embryo culture supernatant into the uterine cavity did not improve the pregnancy rate of day 3 embryo transfer in patients who underwent in vitro fertilization-embryo transfer: a randomized clinical trial
    Fertil Steril. 2010 May 1;93(7):2216-21. Epub 2009 May 12.
  • Fall in implantation rates following ICSI with sperm with high DNA fragmentation
    B.E.Speyer Human Reproduction 2010 UK
  • Effect of gonadotropins on oocyte maturation in vitro : an animal model
    Fertility and sterility Vol.93, No.5, March 15,2010 New York
  • Evaluation of the immature human oocytes fro unstimulated cycles in polycystic ovary syndrome patients using a novel scoring system
    Fertility and sterility Vol.93, No.7, May 1,2010 New York
  • Dynamic microfunnel culture enhancecs mouse embryo development and pregnancy rates
    Y.S.Heo Human Reproduction 2010  USA
  • Primate model of metaphase I oocyte in vitro maturation and the effects of a novel glutathione donor on maturation, fertilization, and blastocyst development
    C Eliza Fertility and Sterility,Vol.95,No.4,March 15,2011 Australia
  • Selection of viable spermatozoa from testicular biopsies: a comparative study between pentoxifylline and hypoosmotic swelling test
    M Vijay Fertility and Sterility Vol.95, No.2, February 2011 India
  • Influence of embryo transfer on blastocyst viability
    Grygoruk C et al., Fertil Steril. 2011 Mar 15;95(4):1458-61. Epub 2010 Jun 12.,Poland
  • In vitro maturation (IVM) of murine and human germinal vesicle (GV)-stage oocytes by coculture with immortalized human fallopian tube epithelial cells
    HJ et al., Fertil Steril. 2011 Mar 15;95(4):1344-8. USA
  • Efficancy of oocyte vitrification combined with blastocyst stage taransfer in an egg donation program
    Human reproduction, vol.26, No.4 pp.782-790, 2011, Peru
  • Aoutomatic user-independent zona pellucida imaging at the oocyte stage allows for the prediction of preimplantation development
  • Ultrastructual evaluation of human metaphaseⅡ oocytes after vitrification:closed versus open devices
  • Vitrification of human ovarian tissue:effect of different solutions and procedures
    Fertility and Sterility 2011 Belgium
  • Oocyte maturation failure:a syndrome of bad eggs
    Fertility and Sterility 2011 Maryland (USA)
  • In vitro maturation of human germinal vesicle-stage oocytes:role of epidermal growth factor-like growth factors in the culture medium
    Human Reproduction 2011 Israel
    「ヒトGV卵子成熟におけるIVM培地への上皮細胞増殖因子(EGF)like growth factor 添加の役割」
  • Successful treatment of unresponsive thin endometrium
  • Influence of embryo sex on development to the blastocyst stage and euploidy
    Fertility and Sterility 2011 Massachusetts
  • Effect of embryo density and microdrop volume on the blastocyst development of mouse two-cell embryos
    Fertility and Sterility 2011 Thailand
  • Role of semen analysis in subfertile couples
    Fertility and Sterility 2011 Netherland
  • Morphological nucler integrity of sperm cells is associated with preimplantation genetic aneuploidy screening cycle outcomes
    Fertility and Sterility 2011 Brazil
  • Dose cessation of progesterone supplementation durring early pregnancy in patients treated with recFSH/GnRH antagonist affect ongoing pregnancy rates? A randomized controlled trial
  • Comparative analysis of tha metaphase Ⅱ spindle of human oocytes through polarized light and high performnce confocal microscopy
    Fertility and Sterility 2010 Italy
  • Comprehensive chromosome screening of polar bodies and blastocysts from couples experiencing repeated implantation failure
    Fertility & Sterility Vol. 94, No. 3, August 2010, New Jersey
  • Treating women under 36 years old without top-quality embryos on day 2: a prospective study comparing double embryo transfer with single blastocyst transfer
    (Day 2 にTQEの無い35歳以下の女性の治療:2個の胚移植と1個の胚盤胞移植の比較)
  • Zona pellucida-induced acrosome reaction in human spermatozoa is potentiated by glycodelin-A via down-regulation of extracellular signal-regulated kinases and up-regulation of zona pellucida-induced calcium influx
  • Aberrant spindle structures responsible for recurrent human metaphase Ⅰoocyte arrest with attempts to induce meiosis artificially
  • Prediction of pregnancy rate by blastocyst morphological score and age, based on 1,488 single frozen-thawed blastocyst transfer cycles
  • Differential pH in embryo culuture
  • The effectiveness of intracytoplasmic sperm injection combined with piezoelectric stimulation in infertile couples with total fertilization failure
  • Duration of progesterone-in-oil support after in vitro fertilization and embryo transfer: a randomized, controlled trial
    IVF、ET後のプロゲステロン補充期間 無作為管理下試験
  • The effect of modified quarter later-assisted zona thinning on the implantation rate per embryo in frozen/vitrified-thawed/warmed embryo transfer cycles:a prospective randomized controlled trial
  • Pregnancy outcomes in 188 French cases of prenatally diagnosed Klinefelter syndrome
  • The use of morphokinetics as a predictor of embryo implantation
  • Human meiotic progression and recombination are affected by Bisphenol A exposure during in vitro human oocyte development
  • In vitro development of secondary follicles from cryopreserved rhesus macaque ovarian tissue after slow-rate freeze or vitrification
  • Microarray assessment of methylation in individual mouse blastocyst stage embryos shows that in vitro culture may have widespread genomic effects
  • Ultrastructure and intracellular calucium response during activation in vitrified and slow-frozen human oocytes
  • Analysis of global gene expression following mouse blaM.G.Larman 2011 Human Reproduction stocyst cryopreservation
  • Factors predicting the cumulative outcome of IVF/ICSI treatments: a multivariable analysis of 2450 patients
  • Implications of blood type for ovarian reserve
  • MicroRNAs are associated with human embryo implantation defect
  • Trophectoderm morphology: an important parameter for predicting live birth after single blastocyst transfer
  • Clinical outcomes and development of children born after intracytoplasmic sperm injection (ICSI) using extracted testicular sperm or ejaculated extreme severe oligo-astheno-teratozoospermia sperm:a comparactive atudy
  • comparison of in vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal crod injuries
  • The competence of germinal vesicle oocytes is unre;ated to nuclear chromatin configuration and strictly depends on cytoplasmic quantity and quality in the cat model
  • Implications of blood type for ovarian reserve
  • MicroRNAs are associated with human embryo implantation defects
  • Glucose consumption of single post-compaction human embryos is predictive of embryo sex and live birth outcome.
  • A pragmatic RCT of conventional versus increased concentration sucrose in freezing and thawing solutions for human embryos.
    ヒト胚に対する凍結融解液へのsucroseの通常濃度添加 対 強化濃度添加の実践的RCT
  • Comparison of Cryotip vs. Cryotop for mouse and human blastomere vitrification
    Fertility and Sterility 2012
  • Developmental potential of embryos from intracytoplasmic sperm injection cycles containing fragmented oocytes.
  • Selection of high-potential embryos by culture in poly (dimethylsiloxane) microwells and time-lapse imaging
  • Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen activators during interplay between gametes.
  • Semen analysis:looking for an upgrade in class
  • Phospholipase C-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection
  • Nitric oxide synthase and tyrosine nitration in idiopathic asthenozoospermia: an immunohistochemical study
  • Superoxide dismutase content in sperm correlates with motility recovery after thawing of cryopreserved human spermatozoa
    Mariano G.Buffone,Ph.D. Fertility and Sterility Vol.97,No.2 February 2012 America
  • Human sperm head vacuoles are physiological structures formed during the sperm development and maturation process
    Fertility & Sterility 2012 USA
  • Effects of low molecular weight heparin and heparin-binding epidermal growth factor on human trophoblast in first trimester
    Fertility & Sterility, Vol. 97, No. 3, 2012, China
  • Is the zona pellucida thickness of human embryos influenced by women’s age and hormonal levels?
  • Trophectoderm morphology significantly affects the rates of ongoing pregnancy and miscarriage in frozen-thawed single-blastocyst transfer cycle in vitro fertilization
    Fertil Steril. 2012 Aug 98(2):
  • The effect of GM-CSF on development and aneuploidy in murine blastocysts.
    Human Reproduction,vol.27,No.6 pp.1590-1595,2012 UK
  • 「Day3 embryo selection by metabolomic profiling of culture medium with near-infrared spectroscopy as an adjunct to morphology: a randomized controlled trial.」
    Human Reproduction, Vol27, No8pp.2304-2311, 2012 USA
  • 「Sperm DNA fragmentation index does not correlate with the sperm or embryo aneuploidy rate in recurrent miscarriage or implantation failure patients」
    Human Rproduction, Vol27, No7pp. 1992-1929, 2012 Spain
  • Full in vitro fertilization laboratory mechanization: toward robotic assisted reproduction?
    Fertility & Sterility, Vol. 97, No. 6, 2012, Denmark
  • Age-associated alterration of oocyte-specific gene expression in polar bodies:potential markers of oocyte competence
    Fertility & Sterility, Vol. 98, No. 2, 2012, Cicago
  • Assisted oocyte activatoin is not beneficial for all patients with a suspected oocyte-related activation deficiency
    Human Reproduction, Vol.27, No.7, pp.1977-1984 2012 Belgium
  • Effects of combined epidermal growth factor, brain-derived neurotrophic factor and insulin-like growth factor-1 on human oocyte maturation and early fertilized and cloned embryo development
  • Heparin enhances protamine disulfide bond reduction during in vitro decondensation of human spermatozoa
  • Difference in transcriptomic profiles of fuman cumulus cells isolated from oocytes at GV、MⅠ、MⅡ stage after in vivo and in vitro oocyte maturation
  • Further evidence that culture media affect perinatal outcome:findings after transfer of fresh and cryopreserved embryos
  • Exposure to lipid-rich follicular fluid is associated with endoplasmic reticulum stress and impaired oocyte maturation in cumulus-oocyte complexes
    Fertility and Sterility 2012.Australia
  • Outcomes of vitrified early cleavage-stage and blastocyst embryos in a cryopreservation program: evaluation of 3,150 warming cycles
    Fertility and Sterility 2012.Spain
  • The value of chromosomal analysis in oligozoospermic men
    Fertility and Sterility 2012. Netherlands
  • Sperm vacuoles are linked to capacitation and acrosomal status.
    Human Reproduction Vol.27,No.10 pp.2927-2932,2012 France
  • BMI-related metabolic composition of the follicular fluid of women undergoing assisted reproductive treatment and the consequences for oocyte and embryo quality
  • Preimplantation genetic diagnosis: a systematic review of litigation in the face new technology
  • Successful delivery derived from vitrified-warmed spermatozoa from a patient with nonobstructive azoospermia
  • Limited implantation success of direct-cleaved human zygotes:a time-lapse study
    Fertility and Sterility 2012 Denmark
  • Application of a ready-to-use calcium ionophore increases rates of fertilization and pregnancy in severe male factor infertility
    Fertility and Sterility 2012 Germanyk
  • The effect of maternal age on chromosomal anomaly rate and spectrum in recurrent miscarriage
    Fertility and Sterility 2012 Germanyk
  • Motile sperm organelle morphology evaluation-selected globozoospermic human sperm with an acrosomal bud exhibits novel patterns and higher levels of phospholipase C zeta
  • Altered gene expression profile in cumulus cells mature M2 oocytes from patients with polycystic ovary syndrome
    Human Reproduction France
  • Follicle microenvironment-associated alterations in gene expression in the mouse oocyte and its polar body
    Fertility and Sterility U.S.A
  • Blastocyst preimplantation genetic diagnosis(PGD) of a mitochondrial DNA disorder
    Fertility and Sterility New York
  • Trophectoderm grade predicts outcome of single-blastocyst transfers Fertility and Sterility Maryland
    Fertility and Sterility 2013 Denmark
  • Effect of oxygen concentration on human embryo development evaluated by time-lapse monitoring
    Fertility and Sterility 2013 Denmark
  • In vitro development and chromosome constitution of embryos derived from monopronucleated zygotes after intracytoplasmic sperm injection.
    Fertility and Sterility,Vol.99,No.3,March,2013 Spain
  • Impact of follicular G-CSF quantification on subsequent embryo transfer decisions : a proof of concept study
    Human Reproduction Belgium
  • Biomarkers identified with time-lapse imaging : discovery, validation, and practical application
    Fertility and Sterility USA
  • Embryo whose polar bodies contain isolated reciprocal chrosome aneuploidy are almost always euploid
  • Intracytoplasmic morphologically selected sperm injection versus intracytoplasmic sperm
    injection:astep toward a clinical algorithm
    IMSI vs ICSI:アルゴリズムに向けての段階
  • Use of hyaluronan in the selection of sperm for intracytoplasmic sperm injection (ICSI): significant improvement in clinical outcomes-multicenter, double-blinded and randomized controlled trial
  • Effect of ICSI on gene expression and development of mouse preimplantation embryos
  • Optimaizing human oocyte cryopreservation for fertility preservation patients:sould we mature then freeze or freeze then mature?
    Fertility and Sterility New York 2013
  • Is the nuclear status of embryo an independent factor to predict its ability to develop to them?
    Fertility and Sterility France 2013
  • 「Semi-automated morphometric analysis of human embryos can reveal correlations between total embryo volume and clinical pregnancy
  • Human trophectoderm cells are not yet committed
  • Analysis if metabolism to select viable human embryos for transfer
  • Fresh embryo transfer versus frozen embryo transfer in in vitro fertilization cycles:a systematic review and meta-analysis
  • Cryoprotectants up-regulate expression of mouse oocyte AQP7、which facilitates water diffusion during cryopreservation
    Fertility and Sterility 2013 China
  • Evaluation of an sffective multifaceted implementation strategy for elective single embryo transfer after in vitro fertilization
    Human Reproduction 2013 Netherlan
  • Sequential comprehensive chromosome analysis on polar bodies, blastomeres and trophoblast: insights into female meiotic errors and chromosomal segregation in the preimplantation window of embryo development
    Human Reproduction, 2013, Italy
  • Vitrification preserves proliferstion capacity in human spermatogonia
  • Diagnostic and prognostic value of calcium oscillatory pattern analysis for patients with ICSI fertilization failure
  • Novel technologies for selecting the best sperm for in vitro fertilization and intracytoplasmic sperm injection
    Fertility and Sterility 2013 US
  • Perfringolysin O as a useful tool to study human sperm physiology
    Fertility and Sterility 2013 US
  • Preimplantation genetic screening using fluorescence in situ hybridization in patients with repetitive implantation failure and advanced maternal age: two randomized trials
    C Rubio et al, Fertil Steril. 2013 Apr;99(5):1401-07. ,Spain
  • Preimplantation human blastocysts release factors that differentially alter human endometrial epithelial cell adhesion and gene expression relative to IVF success
    Human Reproduction, Vol. 28, No. 5, 2013, Australia
    ヒト胚盤胞が放出する子宮内膜上皮細胞の接着と遺伝子発現を変化させる因子についてHuman Reproduction, Vol. 28, No. 5, 2013, Australia
  • FISH reanalysis of inner cell mass and trophectoderm samples of previously array-CGH screened blastocysts shows high accuracy of diagnosis and no major diagnostic impact of mosaicism at the blastocyst stage.
    Human Reproduction, Vol.28, No.8 2013 USA
  • Dose intracytoplasmic morphologically selected sperm injection improve embryo development?A randomized sibling-oocyte study
    Human reproduction 2013.Belgium
  • Sperm vacuoles negatively affect outcomes in intracytoplasmic morphologically selected sperm injection in terms of pregnancy,implantation,and live-birth rates
    Fertility and Sterility Vol 100 2013
  • Evolution of aneuploidy up to Day 4 of human preimplantation development
    Human reproduction 2013.Belgium
  • Polar body analysis by comparative genomic hybridization accurately predicts aneuploidies of maternal meiotic origin in cleavage stage embryos of woman of advanced maternal age
    Human reproduction 2013 UK
  • Lower intracellular concentration of cryoprotectants after vitrification than after slow freeging despite exposure to higher concentration of cryoprotectant solutions
    Human reproduction 2013
  • What is the best cryopreservation protocol for human testicular tissue banking?
    Human reproduction 2013 Belgium