定期的に最新の知識・技術を取り入れるため、英文抄読会を行っています。
海外で発表された報告についてスタッフ同士意見交換することにより、スタッフのレベルの向上を図っております。
英文抄読会の内容一覧
- Efficient treatment of infertility due to sperm DNA damage by ICSI with testicular spermatozpna．
Human Reproduction Vol.20, No.1pp.48, 226-230, 2005
精巣精子を用いてのICSIを行なうことにより、精子のDNA損傷を軽減することができる - Comparison of the survival of human biopsied embryos after cryopreservation with for different methods using non-transfarable embryos.
Human Reproduction Vol.20,a No.6pp.1615-1618, 2005
移植に適さなかったバイオプシー後のヒト胚について、4種の凍結法での生存率の比較 - High magnitude of light retardation by the zona pellucida is associated with conception cycles.
Hum Reprod. 2005 Jun;20(6):1596-606.
Poloscopeを用いて測定した、透明帯内層の光学的遅延量は妊娠と胚発育を反映し、ARTにおいて胚評価をする上で新しい指票となる。 - Occurrence and development consequences of vacuoles thoughout preimplantation devwlopment Fertility and Sterility vol.83,No.6,June 2005
移植までの成長過程で空胞が発生や発育に与える影響 - Observational clinical follow-up of oocyte cryopreservation using a slow-freezing method with 1,2-Propanediol plus sucrose followed by ICSI
Human Reproduction Vol.20，No.7.pp.1975-1980,2005
プロパンダイオールとスクロースを用いた卵子緩慢凍結と融解後のICSIをするための最適条件とは？ - Frequency of aneuploidy in sperm from patients with extremely severe male factor infertility.
Human Reproduction Vol.20,No.8 pp.2140-2152,2005
重度男性因子不妊患者の精子における異数性の頻度 - Promising results with 306 single blastocyst transfers.
Anueploid analysis of tripronuclear zygotes derived from in vitro fertilization and intracytoplasmic sperm injection in humans Fertility and Sterility Vol.83, No.6, June 2005
306例の単胚盤胞移植に期待される成果
3PN胚の異数倍数体分析はヒトのIVFとICSIに由来する - Cryoloop vitrification of rabbit oocytes
Human Reproduction Vol.20,No.7 pp.1969-1974,2005
クライオループを用いたウサギ卵のガラス化保存 - Treatment option for sperm- or oocyte- related fertilization failure: assisted oocyte activation following diagnostic heterologous ICSI.
精子または卵子による受精不成功例の治療法の選択：異種ICSIでの診断による卵子活性化
Hum Reprod. 2005 Aug;20(8):2237-41. - Early pronuclear breakdown is a good indicator of embryo quality and viability
Fertility and Sterility Vol.85, No.4, October 2005
早期前核は胚の質や能力のよい指標である - The use of the modified hypo-osmotic swelling test for the selection of immotile testicular spermatozoa in patients treated with ICSI : a randomized controlled study
Human reproduction 2005
TESE時の非運動精子を選別する際の改良型HOSテストの効果について～無作為検討～ - Relationship between pre-embryo pronuclear morphology (zygote score) and standard day 2 or 3 embryo morphology with regard to assisted reproductive technique outcomes.
Fertil Steril. 2005 Oct;84(4):900-9.
前核形態での評価は分割胚形態に比べてよくなかった - Use of both earrly cleavage and day2 mononucleation to predict embryos with high implantatioon potential in intracytoplasmic sperm injection cycles
Fertil Steril. 2005 Nov;84(5):1411-1415.
ICSI周期において高い着床能力を持つ胚を予想するための初期分割とDay2の単核形成の評価 - Comparision of pronuclear zygote morphology and early cleavage status of zygote as additional criteria in the selection of day3 embyos: a randomized study
Fertility and Sterility, vol.85, No.2, Feb, 2006
Day3胚選択時における付加的基準としての前核形態とearly cleavage の比較～無作為検討～ - Removal of lysed blastomerea from frozen-thawed embryos improbes implantation and pregnancy rates in frozen embyo transfer cycles
Fertility and Sterility, vol.84, No.6, Dec, 2005
凍結融解胚からの変性した分割球の除去は、凍結胚移植周期において着床率・妊娠率を改善する - Fluorescence in situ hybridization reanalysis of day-6 human blastocysts diagnosed with aneuploidy on day3
Fertility and Sterility, vol.84, No.5, Nov, 2005
Day3でFISH法で異数体と診断された胚盤胞をDay6で再分析 - Value of the sperm deoxyribonucleic acid fragmentation level, as measured by the sperm chromatin dispersion test, in the outcome of in vitro fertilization and intracytoplasmic sperm injection
Fertillity and Sterility Vol.85,N0.2, February 2006.
精子染色質分散試験によって測定による体外受精とICSI結果と精子DNAフラグメンテーションのレベル - Pregnancies and live births after trophectoderm biopsy and preimplantation genetic testing of human blastocysts
FERTIRRITY AND STERILITY VOL.84, NO.6, DECEMBER 2005
外細胞層の生検と人胚盤胞の着床前遺伝子診断後の妊娠および出生について - Confocal microscopic analysis of the spindle and chromosome configurations of human oocytes matured in vitro
Fertillity and Sterility Vol.85,N0.4, April 2006.
ヒト体外成熟卵における紡錘体と染色体形状の共焦点顕微鏡分析 - Randomized comparison of two different blastocyst grading systems
Fertillity and Sterility VOL.85, NO.3, March 2006
2つの異なる胚盤胞評価システムの無作為比較 - Title:The use of recombinant LH (lutropin alfa) in the late stimulation phase of assisted reproduction cycles: double blind, randomized, prospective study
Human Reproduction Vol.21, No.1 pp90－94, 2006
ART周期排卵誘発後期でのリコンビナントLH（レトロピンアルファ）の使用；二重盲検・無作為・前方的研究 - Title:Urinary follicle-stimulating hormone (FSH) in more effective than recombinant FSH in older women in a controlled randamized study
Fertility and Sterility Vol.85, No.5, May 2006
高齢女性には、尿由来FSHの方がリコンビナントFSHよりも有用である（コントロールランダム化試験） - Title:Towards defining parameters for a successful single embryo transfer in frozen cycles
Human Reproduction Vol.21, No.5 pp.1179- 1183, 2006
凍結周期における成功する単胚移植のパラメーター定義に向けて - Mitochondrial content reflects oocyte variability and fertilization outcome.
Fertil Steril. 2006 Mar;85(3):584-91.
ミトコンドリア容量は卵子生存能力と受精能を反映する。 - Aseptic vitrification of human germinal vesicle oocytes using dimethyl sulfoxide as a cryoprotectant
Fertility and Sterility Vol.85, No.3, March 2006
凍結保護剤としてdimethyl sulfoxide (DMSO)を用いたヒトGV卵の無菌的凍結保存 - Use of a medium buffered with N-hydroxyethylpiperazine-N-ethanesulfonate(HEPES)
introcytoplasmic sperm injection procedures is detrimental to the outcome of in vitro fertilization. ICSI時のHEPESバッファードメディウムの使用が結果に及ぼす影響について
Fertility and sterility Vol.85,No.5,2006
- ICSI outcomes in obstructive azoospremia:influence of the origin of surgically retrieved spermatozoa and the cause of obstruction
Human Reproduction vol.21,No4pp.1018
閉塞性無精子症におけるICSIの結果：外科的回収精子の部位と閉塞の原因の影響 - Morphological scoring of human pronuclear zygotes for prediction of pregnancy outcome
Human Reproduction October 2005
不特定患者における選択的単胚移植は多胎を防ぐが、2個の胚を移植するより有意に妊娠率が低い - Randomized single versus double embryo transfer: obstetric and paediatric outcome
and a cost-effectiveness analysis
Human Reproduction October Vol.21, No.1, 2006
無作為の単胚移植と複数胚移植：産婦人科及び小児科での結果と費用効果の分析 - Role of total antioxidant capacity in the differential growth of human embryos in vitro
Fertility and Sterility Vol.86,No.2,August 2006,Canada
体外でのヒト胚発育の差における抗酸化能力の役割 - Cryopreserved embryo transfers suggest that endmetrical receptivity may contribute to reduced success rates of later developing embryo
Fertility and Sterility Vol.86 No4, October.2006
凍結保存胚移植から、発育が遅い胚の成功率低下の原因は子宮内膜の受容性にある可能性が示唆された - Nuclear and cytoplasmic maturation of in vitro matured human oocytes after temporary nuclear arrest by phosphodiesterase 3-inhibitor
Human Reproduction Vol.22, No.5 pp. 1239-1246, 2007
ホスホジエステラーゼ3インヒビターによる減数分裂の一時的停止を行ったヒトIVM卵の細胞質と核の成熟について - Limited value of morphological assessment at days 1 and 2 to predict blastocyst development potential:A prospective study based on 4042 embryos
Human Reproduction Vol.22,No.7 pp. 1978- 1981,2007
胚盤胞発育能の指標のためのDay1/2での形態評価の限界値：4042の胚における前方視的研究 - Oocyte euploidy, pronuclear zygote morphology and embryo chromosomal complement
Human Reproduction Vol.22, No.1 pp. 241-249
卵子の正倍数性、前核形態と胚染色体対 - Variable aneuploidy mechanisms in embryos from couples with poor reproductive histories undergoing preimplantation genetic screening.
Hum Reprod. 2007 Jul;22(7):1844-53. 2007
着床前遺伝子スクリーニングを行なった予後不良患者の胚の異数性メカニズム - Morphologic parameters of early cleavage-stage embryos that correlate with fetal development and delivery : prospective and applied data for increased pregnancy rates
Human Reproduction Vol. 22, No. 1 pp230-240, 2007
胎児発生または出産率に影響する初期分割期の胚評価について～妊娠率増加を見込んだ前方視的検討～ - Metabolism of human embryos following cryopreservation : Implications for the safety and selection of embryos for transfer in clinical IVF
Human Reproduction Vol.22, No.3 pp. 829-835, 2007
凍結保存後のヒト胚の代謝作用：臨床IVFにおける安全な着床と移植用の胚選択 - Exposure to human chorionic gonadotropin during in vitro maturation does not improve the maturation rate and developmental potential of immature oocytes from patients with polycystic ovary syndrome
Fertility and Sterility Vol.89, No. 1, January 2008
体外成熟培地へのヒト絨網膜性腺刺激ホルモン（hCG）の添加による成熟率上昇またはPCO患者から得られた未成熟卵子の発生能の上昇はみられなかった - Osmotic responses and tolerance limits to changes in external osmolalities, and oolemma permeability characteristics, of human in vitro matured MⅡ oocytes
Human Reproduction Vol.22, No.7 pp.1959-1972, 2007
ヒト体外成熟MⅡ卵子における浸透反応と外部の浸透圧変化に対する耐性限界、そして透明帯の浸透性の特徴 - Contrasting patterns in in vitro fertilization pregnancy rates among fresh autologous , fresh oocyte donor , and cryopresevrved cycles with the use of day 5 or day6 blastocysts may reflect differences in embryo-endometrium synchrony
Fertility and Sterility Vol.89,No.1 January 2008
新鮮卵子、新鮮ドナー卵子、凍結周期におけるDay5あるいはDay6胚盤胞の妊娠率の対照的なパターンは胚と子宮内膜の同期性において違いを示すかもしれない - Is fine morphology of the human sperm nuclei affected by in vitro incubation at 37℃?
Fertility and Sterility Vol.88,No.6,December 2007
人の精子核の正常な形態は37度での体外培養により影響を受けるか？ - The relative contribution of assisted reproductive technologies and ovulation induction to multiple births in the United States 5 years after the Society for Assisted Reproductive Technology/American Societyfor Reproductive Medicine recommendation
to limit the number of embryos transferred.
Fertility and Sterility Vol.88,No.6,December 2007
SART/ASRM勧告による移植胚数の制限から5年間の米国におけるARTの貢献と排卵誘発による多胎出産の関係 - Early cleavage does not predict treatment outcome following the use of GnRH antagonists in women older than 35
FERTIRRITY AND STERILITY VOL.88, NO.6, December 2007
35歳以上のGnRHアンタゴニストを使用した患者では、早期分割は治療結果の指標とならない - Alterd composition of the cumulus-oocyte complex matrix during in vitro maturation of oocytes
Human Reproduction Vol. 22, No. 11 pp. 2842-2850, 2007
卵子体外成熟時における卵子卵丘細胞複合体の組織変化について - Day－3 embryo morphology predicts euploidy among older subjects
Fertility and Sterility Vol.89, No.1, January 2008
Day3胚形態は高齢患者間の正倍数体を予測する - Permeability of human oocytes to and their survival and spindle configurations after slow cooling cryopresevation
Human Reproduction Vol.22,No.10 pp.2776-2783,2007
ヒト卵子におけるエチレングリコールの透過性と緩慢凍結後の生存とスピンドル形態 - Differences in ovarian function parameters between Chinese and Caucasian oocyte donors: do they offer an explanation for lower IVF pregnancy rates in Chinese women?
Human Reproduction Vol.22,No.11 pp.2879-2882,2007
中国人とコーカサス人の卵子ドナーでの卵巣機能パラメーターの違い：中国人女性での低いIVF妊娠率の説明となりうるか？ - Oxygen concentration during mouse oocyte in vitro maturation affects embryo and fetal development.
Human Reproduction Vol.22,No.10 pp2764-2775 2007
体外成熟におけるマウス卵の酸素濃度は胚と胎児の発育に影響する。 - Adequate ovarian follicular status does not prevent the decrease in pregnancy rates associated with high sperm DNA fragmentation
FERTIRRITY AND STERILITY VOL.89, NO.1, January 2008
適切な卵胞状態でも精子DNAの断片化に関する妊娠率の低下は防ぐことができない - Isolated teratozoospermia dose not affect in vitro fertilization outcome and is not an indication for intracytoplasmic sperm injection
Fertility and Sterility Vol.88, No.6, December 2007
奇形精子症だけでは体外受精の結果に影響を及ぼさず、顕微授精の必要はない - Live birth rates after tranfer of equal number of blastocysts or cleavage- stage embryo in IVF.. A systematic review and meta-analysis
Human Reproduction Vol.23,No.1pp.91-99,2008
IVFにおける分割期胚あるいは胚盤胞期胚を同数移植後の出生率：レビューとメタアナリシス - Human blastocyst morphological quality is significantly improved in embryos classified as fast on day 3(≧10cells ), bringing into question current embryological dogma
Fertility and Sterility Vol.89,No.2 2008
D3に発育が早かった胚の胚盤胞の形態学的質は有意に高い、現在の発生学の定説への疑問 - Failed fertilization after ICSI and spermiogenic defects
Fertility and Sterility Vol.89,No.4,April 2008
ICSI後の受精不成功と精子形成に関する異常 - Randomized double-blind comparison of laser zona pellucida thinning and breaching in frozen-thawed embryo transfer at the cleavage stage.
Fertility Sterility Vol.89,No5,May 2008
分割ステージでの凍結融解胚移植における、レーザーによる透明帯の薄化法および貫通法のランダム化ダブルブラインドの比較 - Do sperm DNA integrity tests predict pregnancy with in vitro fertilization?
Fertility Sterility Vol.89,No4,April 2008
精子中DNAの完全性のテストは体外受精での妊娠を予測するか？ - Predictors of ongoing pregnancy after single-embryo transfer following mild ovarian stimulation for IVF
Fertility and Sterility Vol.89, No.5, May 2008
IVFで軽度の卵巣刺激を受けて単胚移植した後の妊娠継続の指標 - Day 4 versus day3 embryo transfer:a prospective study of clinical outcomes
Fertility and Sterility Vol. 89, No. 3, March 2008
Day4とDay3の胚移植を比べて：予測される臨床成績について - Genetic screening in 2,710 infertile candidate couples for assisted reproductive techniques : results of application of Italian guidelines for the appropriate use of genetic tests
Fertility and Sterility Vol.89 No.4 April 2008
ARTを行う2,710の不妊カップルの遺伝子スクリーニング：遺伝子試験の適切な使用のためのイタリアのガイドラインの適用結果 - Diagnostic efficiency, embryonic development and clinical outcome after the biopsy of one or two blastomeres for preimplantation genetic diagnosis.
Hum Reprod. 2008 Mar;23(3):493-8.
着床前遺伝子診断のための1個または2個の割球の生検後の診断効率と胚発育および臨床成績 - Integrity rate of pronuclei after cryopreservation of pronuclear-zygotes as a criteria for subsequent embryo development and pregnancy
Human Reproduction Vol.23, No.4, pp.819-826, 2008
胚発育および妊娠の指標としての前核期胚凍結保存後の前核の完全性評価 - Vitrification of preimplantation genetically diagnosed human blastocysts and its contribution to the cumulative ongoing pregnancy rate per cycle by using a closed device
Fertility and Sterrility Vol.89, No.4, April 2008
PGD後のヒト胚盤胞のガラス化と密閉装置を使った周期ごとの累積継続妊娠率に対する貢献 - Day4 embryo selection is epual to Day5 using a new embryo scoring system validated in single embryo transfers
Human Reproduction Vol.23, No.7, pp.1505-1510, 2008
単胚移植による新しい胚スコアリングシステムを用いたDay4胚の選択はDay5と同等である - Human immature oocytes grow during culuture for IVM
Human Reproduction Vol.23, No.1, pp.37-45, 2008
ヒト未熟卵子は体外培養中に成長する - Autologous mature follicular fluid:its role in in vitro maturation of human cumulus-removed oocytes
Fertility and Sterility Vol.90, No.4, October 2008
自己由来の成熟卵胞液：ヒトの裸化した卵子の体外成熟での役割 - The impact of spermatozoa preincubation time and spontaneous acrosome reaction in intracytoplasmic sperm injection: a controlled randomized study
Fertility and Sterility Vol.90, No.3, September 2008
細胞質内精子注入法においての精子の前培養時間と自発的アクロソーム反応の影響：無作為化比較分析 - Severe cytoplasmic abnormalities of the oocyte decrease cryosurvival and subsequent embryonic development of cryopreserved embryos
Human Reproduction Vol.23, No.8, pp.1778-1785, 2008
卵子の深刻な細胞質異常は凍結胚の融解後生存と胚発生を低下させる - A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification:vitrification is associated with higher survival, metabolism and blastocyst formation
Human Reproduction Vol.23, No.9 pp. 1976-1982, 2008
ヒトD3胚における緩慢凍結法もしくはガラス化凍結法の無作為試行：ガラス化は生存性、代謝能、胚盤胞形成と高い関連性がある - Impact of early cleaved zygote morphology on embryo development and in vitro fertilization-embryo transfer outcome: a prospective study
Fertility and Sterility Vol.89,No.6 June 2008
胚発育における早期分割胚の影響と体外受精胚移植結果 - Metabolic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection
Human Reproduction 2008, Vol.23,No.7
胚の生存能力の分析方法としてNIR分光器を用いた代謝プロファイリング：非侵襲的な新しい胚選択方法 - Role of coculture in human in vitro fertilization: a meta-analysis
Fertility and Sterility 2008, Vol.90,No.4, October
ヒト体外培養系における共培養の効果について - Cryopreservation of human embryos by vitrification or slow freezing: a systematic review and meta-analysis
Fertility and Sterility 2008, Vol.90,No.1,July
ヒト胚のガラス化または緩慢の凍結方法：系統的レビューとメタ分析 - Effect of hyaluronan-enriched transfer medium on implantation and prednancy rates after day3 and day5 embryo transfers:a prospective randomized study
Fertility and sterility vol. 90 No3 September 2008
ヒアルロン酸に富んだ移植メディウムのDay3あるいはDay5胚移植の妊娠、着床率への影響 - How viable are zygotes in which the PN are still intact at 25 hours?
Fertility and Sterility Vol.90, No.3, September 2008
25時間で前核が完全に見えている胚の生存能力はどのくらいか？移植胚選択への影響 - Freezing within 2h from oocyte retrieval increases the efficiency of human oocyte cryopreservation when using a slow freezing/rapid thawing protocol with high sucrose concentration
Human Reproduction 2008, Vol.23, No.8
高いスクロース濃度での緩慢凍結、急速融解における採卵後2時間の凍結はヒト卵子凍結の有効性を向上する - Sperm head`s birefringence : a new criterion for sperm selection
Fertility and Sterility Vol.90, No.1, July 2008
精子頭部の複屈折：精子選択のための新しい判断基準 - Quantitative morphometrical characterization of human pronuclear zygotes
Human Reproduction Vol.23, No.9 pp.1983-1992, 2008
ヒト前核の定量的計測の評価 - Dopamine agonist administration causes a reduction in endometrial implants through modulation of angiogenesis in experimenrally induced endometrisis
Human Reproduction; 24: 1025-, 2009
ドーパミン作動薬は実験的子宮内膜症において、血管新生を抑制することにより移植した子宮内膜組織を減少させる - Choosing a culture medium: making informed choices
Fertility and Sterility Vol. 90, No. 3, 2008
培養液を選ぶときの注意点 - Permature ovarian failure and dehydroepiandrosterone
FERTIRRITY AND STERILITY VOL.91, NO.2, February 2009
早発卵巣不全とDHEA - Location of endometrial polyp and pregnancy rate in infertility patients
FERTIRRITY AND STERILITY VOL.90, NO.1, July 2008
子宮内膜ポリープの位置と妊娠率 - The plausibility of Helicobacter pylori-related infertility in Japan
FERTIRRITY AND STERILITY VOL.90, NO.3, September 2008
ヘリコバクターピロリに関連した不妊症の日本人での信憑性 - Spindle imaging: a marker for embryo development and implantation
FERTIRRITY AND STERILITY VOL.90, NO.1, July 2008
紡錘体の画像化：胚の発育および着床の指標 - Comparative protein-profile analysis of implanted versus non-implanted human blastocysts
Human Reproduction Vol.23, No.9, 2008
着床ヒト胚盤胞と非着床ヒト胚盤胞のタンパクプロファイル分析による比較 - Soy food and isoflavone intake in relation to semen quality parameters among men from an infertility clinic
Human Reproduction Vol.23,No.11 pp.2584-2590,2008
大豆食品やイソフラボン摂取と精液所見(横断研究) - Food intake and its relationship with semen quality:a case-control study
Fertility and Sterility Vol.91,No.3,March 2009
食事と精液所見(ケースコントロールスタディ) - Acetaldehyde differentially affects the growth of uterine leiomyomata and myometrial cells in tissue cultures
Fertility and Sterility Vol.91,No.2,February 2009
アセトアルデヒド(アルコールの代謝物)」はin vitroで子宮筋腫や子宮筋の発育に影響する - Impact of day3 or day5 embryo transfer on pregnancy rates and multiple gestations
Fertility and Sterility Vol.91,No.5,May 2009
Day3ETあるいはDay5ETが妊娠率および多胎妊娠に与える影響 - Myo-inositol may improve oocyte quality in intracytoplasmic sperm injection cycles.
Fertility and Sterility Vol.91,No.2,February 2009
ミオイノシトールはICSI周期において卵の質を改善するかもしれない - Coiled sperm from infertile patients:characteristics,associated factors and biological implication
Human Reproduction Vol.24,No.6 pp.1288-1295,2009
不妊患者由来のコイル精子：特徴、関連因子、生物学的影響 - Single Day 2 embryo versus blastocyst-stage transfer: a prospective study integrating fresh and frozen embryo transfers
Human Reproduction Vol.24,No.5,2009
Day2または胚盤胞での新鮮単胚移植と凍結単胚移植の比較 - In vitro culture under physiologic oxygen concentration improves blastocyst yield and quality: a prospective randomized survey on sibling oocytes
Fertility and Sterility Vol.91,No.4,April 2009
体外での生理学的酸素濃度が胚盤胞への発生および品質を改善する：同胞卵子の前方視的無作為化調査 - Correlation between DNA damage and sperm parameters: a prospective study of 1633 patients
Fertility and Sterility Vol.91,No.5,May 2009
DNAのダメージと精子のパラメーターの関係：1633人の患者の前方視的研究 - Long-term liquid nitrogen vapor storage of mouse embryos cryopreserved using vitrification or slow cooling
Fertility and Sterility Vol.91,No.5, May 2009
ガラス化凍結および緩慢凍結したマウス胚の液体窒素蒸気中での長期間の保存 - Asian ethnicity is associated with reduced pregnancy outcomes after assisted reproductive technology
Fertility and Sterility Vol.87,No.2,February 2007
アジア人(黄色人種)はART(体外受精)の妊娠率が低い - Does ethnicity influence in vitro fretilization(IVF) birth outcomes?
Fertility and Sterility Vol.91,No.6,June 2009
人種間の相違はIVFの妊娠に影響するか？ - DrIncrease in scrotal tempereture in car drives
Human Reproduction, Vol. 15, No.6, 2000
車の運転における陰のう温度の上昇 - Increase in scrotal temperature in laptop computer users
Human Reproduction, Vol. 20, No.2 ,2005
ラップトップパソコンユーザーの陰のう温度上昇 - Influence of the type of undertrousers and physical activity on scrotal temperature
Human Reproduction, Vol. 20, No.4, 2005
下着の種類と活動性による陰嚢温度への影響 - DNA damage and metabolic activity in the preimplantation embryo
Human Reproduction, Vol. 24, No.1 pp81-91, 2009
着床前胚のDNAダメージと代謝活性 - Effect of triploidy after intracytoplasmic sperm injection on in vitro fertilization cycle outcome
Fertility and Sterility Vol.91 No.1, January 2009
ICSI後の3倍体の体外受精結果への影響 - Electrical activation of oocytes after intracytoplasmic injection:a controlled ramdomized study
Fertility and Sterility Vol.91 No.1, January 2009
ICSI後の電気的卵子活性化：コントロール無作為研究 - A controlled randomaized trial evaluating the effect of lowered incubator oxygen tention on live births in a predominantly blastocyst transfer program
Human Reproduction, Vol. 24, No.2 ,2009
良好胚盤胞において、低酸素培養が正常出産に効果を及ぼすかどうかランダム化試験により評価する - valiation of a disposable plastic Neubauer counting chamber for semen analysis
Fertility and Sterility Vol.91 No., February 2009
精液検査用使い捨て計算盤の評価 - Viability and function of the cryopreserved whole ovary: in vitro studies in the sheep
Human Reproduction,Vol.27,No.7 pp.1684-1694,2009
卵巣全体の凍結保存による生存力と機能:ヒツジでの生体外研究 - Emotional distress of infertile women in japan
Human Reproduction,Vol.16,No.5 ,2001
日本における不妊女性の心理的ストレス - A prospective study of psychosocial stress and fertility in women
Human Reproduction,Vol.12,No.10 ,1997
不妊症女性における心理的ストレスの前方視的研究 - A prospective study of stress among women undergoing in vitro fertilization or gamete intrafallopian transfer
Fertility and Sterility Vol.76 No.4, October 2001
IVFおよびGIFT実施中の不妊症女性における心理的ストレスの前方視的研究 - The effect of selecting oocytes for insemination and transferring all resultant embryos without selection on outcomes of assisted reproduction
Fertility and Sterility Vol.91 No.1, January 2009
媒精のための卵選択と得られた胚全てを移植する効果について - The value of blastocoele re-expantion in the selection of a viable thawed blastocyst for transfer
Fertility and Sterility Vol.91 No.2, February 2009
生育力のある移植用融解胚盤胞選択における再拡張が速い胚盤胞の有用性 - Bacterial endotoxin(LPS)-induced DNA damege in preimplanting embryonic and uterine cells inhibits implantation
Fertility and Sterility Vol.91 No.5, May 2009
着床前胚と子宮細胞においてDNAダメージを誘導するバクテリアエンドトキシン(LPS)は着床を妨げる - L-Carnitine decreases DNA damage and improves the in vitro blastocyst development rate in mouse embryos
Fertility and Sterility Vol.91 No.2, February 2009
L-カルニチンはマウスにおいて、DNAダメージを減少させ、胚盤胞到達率を改善する - New media for culture to blastocyst
Fertility and Sterility Vol.91 No.3, March 2009
胚盤胞培養のための新しい培養液 - Laser zona thinning in women aged ≦37 years: a randomized study
Fertility and Sterility Vol.91 No.4, April 2009
37歳以下女性でのレーザー透明帯菲薄化：無作為化試験 - Viable pregnancies can occur after 24-hour incubation of ejaculated sperm before intracytoplasmic sperm injection
Fertility and Sterility Vol.91 No.4, April 2009
生存妊娠は24時間培養射精精子を用いたICSIから起こる - Optimizing the number of blastocyst stage embryos to transfer on day 5 or 6 in women 38 years of age and older: a Society for Assisted Reproductive Technology database study
Fertility and Sterility Vol.91 No.1, January 2009
38歳以上の女性における5日目、6日目の最適な胚盤胞移植数：補助生殖医学会データベース研究 - Semen preparation methods and apotosis:swim-up versus gradient-density centrifugation technique
Fertility & Stelitity Vol.91, no. 2, February 2009
精子分離方法と精子アポトーシス；swim up vs. 密度勾配遠心法 - A hgih oocyte yield for intracytoplasmic sperm injection treatment is associated with an increased chromosome error rate
Fertility & Stelitity Vol.91, no. 3, March 2009
ICSI周期で採卵数が多くなるにつれ、染色体異常率も増加する - Nuclear maturation and structural components of nonhuman primate cumulus-oocyte complexs during in vivo and in vitro maturation
Fertility & Sterility Vol. 91, No. 5, May 2009
核成熟と卵子卵丘細胞複合体の構造変化について、体外成熟と体内成熟の比較 - Assessment of a new in vitro maturation system for mouse and human cumulus-enclosed oocytes: three-dimansional prematuration culture in the presence of a phosphdiesterase 3-inhibitor
Human Reproduction Vol.24, No.8
マウス・ヒトCEOｓ（卵丘細胞に囲まれた卵子）のための新しいIVMシステムの評価：PDE3-Ⅰ（ホスホジエステラーゼ3-インヒビター）存在下での3次元早熟培養（３D-PMC） - Evoluation of two incubation emvironments-ISO class 8 v.s. ISO class 5-on ICSI cycle outcome
Fertility and Sterility,VOL.91, NO.5, 2009
培養環境評価とICSI周期の成績について-ISOクラス8対ISOクラス5 - Nitric oxide metabolite production in the human preimplantation embryo and successful blastocyst foemation
Fertility and Sterility,VOL.91, NO.4, 2009
酸化窒素代謝産物の産生と胚盤胞形成について - Is there a limit for the number of in vitro fertilization cycles for an individual patient?
Fertility and Sterility,VOL.91, NO.4, 2009
体外受精にリミットはあるのか？ - Modelling the impact of single embryo transfer in a national health service IVF programe
Human Reproduction, VOL.24, NO.1, 2009
全国的な公共医療IVFプログラムによる単胚移植もでるの作成 - Meiotic spindle dynamics in human oocytes following slow-cooling cryopreservation
Human Reproduction, VOL.9, NO.9, 2009
緩慢凍結後のヒト卵減数分裂紡錘体の動力学 - Blastocyst transfer dose not cause a sex-ratio imbalance
Fertility and Sterility,VOL.92, NO.4, 2009
胚盤胞移植では性比率が偏ることはない - Infertility knowledge and attitudes in urban high school students
Fertility and Sterility,VOL.90, NO.6, 2009
都市部の高校生の不妊症に関する知識と態度 - Risk of contamination of germplasm during cryopreservation and cryobanking in IVF units
-
IVFにおける凍結保存による生殖質の汚染の危険性
Human Reproduction, VOL.24, NO.10, 2009
Fresh testicular sperm retrieved from men with spinal cord injury retains equal fecundity to that from men with obstructive azoospermia via intracytoplasmic spem injection
Fertility and Sterility Vol. 92, No. 4
脊髄損傷男性と閉塞性無精子症男性の新鮮精巣精子はICSIで同等の繁殖力を保有する - Artificial oocyte activation with calcium ionophore A23187 in intracytoplasmic sperm injection cycles using surgically retrieved spermatozoa.
Fertility & Stelitity Vol.92, no. 1, July 2009
外科的手法によって採取された精子を用いたICSI周期におけるA23187を用いた人為的活性化処理の効果について - Neonatal outcome after vitrified day3 embryo transfers: a preliminary study
Fertility & Stelitity Vol.92, no. 1, July 2009
凍結Day3胚を移植した場合の生産率について～予備的検討～ - Embryo cryopreservation in the presence of low concentration of vitrification solution with sealed pulled straws in liquid nitrogen slush
Human Reproduction, vol.24 No.4 pp.797-804.2009
sealed pulled strawsを用いた低濃度ガラス化液における液体窒素slushでの胚凍結保存 - Disrupted gene pattern in patients with repeated in vitro fertilization(IVF) failure.
Hum Reprod,Vol.24. No.10, 2009
反復IVF不成功患者における異常な遺伝子パターン - An in vivo cluture system for human embryos using an encapsulation technology:a pilot study.
Hum Reprod,Vol.24. No.4, 2009
カプセル化技術を使ったヒト胚の体内培養システム - The DNA integrity of cryopreserved spermatozoa separated for use in assisted reproductive technology is unaffected by the type of cryoprotectant used but is related to the DNA integrity of the fresh separated preparation
Fertility and Sterility Vol.92,No.3,September 2009
精子凍結のＤＮＡの保全について―精子凍結液の種類については影響をうけないが、凍結前のＤＮＡの完全性による分類については影響をうける - Selection of sperm based on combined density gradient and Zeta method may improve ICSI outcome
Human Reproduction, VOL.24, NO.10, 2009
密度勾配およびゼータ法に基づく精子選別はICSI結果を改善する - Low-oxygen compared with high-oxygen atmosphere in blastocyst culture, a prospctive randomized study
Fertility and Sterility Vol.91,No.6, 2009
胚盤胞培養における低酸素環境と高酸素環境との比較－前方視的無作為研究－ - Comparison of survival and embryonic development in human oocytes cryopreserved by slow-freezing and vitrification
Fertility and Sterility Vol.92,No.4, 2009
緩慢凍結法とガラス化凍結法によるヒト卵の生存性と胚発育の比較 - Live birth sex rations are not influenced by blastocyst-stage embryo transfer.
Fertility and Sterility Vol.92,No.3,September 2009
出生性比は胚盤胞ステージの胚移植によって影響を受けない - Meiotic spindle recovery is faster in vitrification of numan oocytes compared to slow freezing.
Fertility and Sterility Vol.91,No.6,June 2009
ヒト卵子の紡錘体の回復は、緩慢凍結よりもガラス化凍結の方が早い - At what age can human oocytes be obtained?
Fertility and Sterility Vol.92,No.2, 2009
ヒトの卵子を得られる年齢は？ - Activated caspases in thawed epididymal and testicular spermatozoa of patients with congenital bilateral absence of the vas deferens and intracytoplasmic sperm injection outcome
Fertility and Sterility Vol.92,No.2,2009
先天性両側精管欠損症CBAVD患者の融解精巣上体精子と精巣精子の活性型カズパーゼとICSI結果 - Oocyte activation ability correlates with head flatness and presence of perinuclar theca substance in human and mouse sperm
Human Reproduction Vol.24, No.10, 2009
ヒトおよびマウスの卵子活性化能は精子の平坦度と核周囲膜とに相関する - Fertilization and pregnancy using cryopreserved testicular sperm for intracytoplasmic sperm injection with azoospermia
Fertility Sterility Vol.92 No.1 July 2009
無精子症患者における凍結精巣精子ICSIの受精と妊娠 - Selective microsurgical removal of a pronucleus from tripronucler human oocyte to restore diploidy:disregard but valuable?
Frtility Sterility Vol.92 No.3 September 2009
2倍体にするためのヒト3PN卵子の選択的核除去 - Vtrification of immature mouse oocyte using stepwise equilibration before or after in vitro maturation
Fertikity & Stelitity Vol 92,no.3, September 2009
マウスIVM成熟卵子またはマウス未熟卵子の凍結方法別比較 - Assesment of the developmental competence of human somatic cell nuclear transfer embryos by oocyte morphology classification
Fertikity & Stelitity Vol 91,no.6, 2009
卵子形態分類によるヒト体細胞核移植胚の発育能力の評価 - Children born after cryopreservation of embryos or oocytes: a systematic review of outcome data
Human Reproduction Vol.24, No.9, 2009
胚又は卵子凍結保存で生まれた子供たち：転帰に関するデータの系統的レビュー - Assessment of day-3 morphology and euploidy for individual chromosomes in embryo that develop to the blastocyst stage
Fertikity & Stelitity Vol 91,no.6, 2009
Day3における胚の形態および染色体倍数性と胚盤胞への発生率について - Comparison of development and implantation of human embryos biopsied with two different methods: aspiration and Displacement
Fertikity & Stelitity Vol 92,no.2, 2009
PGDの正検方法による発生率と着床率の違い - Preimplantation aneuploid embryos undergo self-correction in correlation with their developmental potential
FERTIRRITY AND STERILITY VOL.92, NO.3, September 2009
着床前の異数性胚はその発育能に相関して自己修正を行う - Rhesus macaque embryos derived from MⅠ oocytes maturing after retrieval display high rates of chromosomal anomalies
Human Reproduction, VOL.24, NO.4, 2009
採卵後のMⅠ卵を成熟させて得られたアカゲザルの胚は高い染色体異常率を示す - Is there an advantage in scoring early embryos on more than one day?
Human Reproduction, Vol.24, No.9 pp. 2104-2113, 2009
初期胚を1日以上でスコアリングすることに効果はあるか - Sperm head morphology is related to high deoxyribonucleic acid stainability assessed by sperm chromatin structure assay
精子頭部形態とデオキシリボ核酸の染色性は関係し精子クロマチン構造分析によって評価される - Evaluation of human sperm function after being cryopreserved within the zona pellucid
透明帯内での凍結後のヒト精子機能の評価 - Reduction of multiple pregnancy rate in a preimplantation genetic diagnosis programme after introduction of single blastocyst transfer and cryopreservation of blastocysts biopsied on day3
D3で生検した胚盤胞の単一胚盤胞移植と胚盤胞凍結の導入後のPGDにおける多胎妊娠の減少 - Cumulus cells and their extracellular matrix affect the quality of the spermatozoa penetrating the cumulus mass
卵丘細胞と細胞外基質は卵丘細胞塊に入り込む精子の質に影響を及ぼす - A randomized controlled study of human serum albumin and serum substitute supplement as protein supplements for IVF culture and the effect on live birth rates
無作為化比較研究によるヒト血清アルブミン(HSA)およびSSS代替血清(SSS)の培地添加が出生率に与える影響 - Location of herniation predicts implantation behaviour of hatching blastocysts.Thomas EBNER, Irmhild GRUBER, Marianne MOSER Austria accepted 2007
「胚盤胞の脱出位置から孵化胚盤胞の着床行動を予期する」 - Preimplantation factor:non-invasive biomarker for embryo selection for in vitro fertilization
着床前ファクター（PIF）：胚選択のための非侵襲的バイオマーカー - Vitrification of isolated human blastomeres
Fertility and Sterility Vol.93,No.2,Junuary,2010 Spain
分離した割球のガラス化保存 - Embrtonic origin of preimplantation factor(PIF): biological activity and partial characterization‐European Society for Human Reproduction and Embryology 1996 from USA
胚性PIFの起源‐生物学的活性と部分的特徴について - Mechanics of human blastocyst hatching in vitroDr Henry SathananthanReproductive BioMedicine Online 2003 Australia
「体外でのヒト胚盤胞Hatchingのメカニクス」 - Automatic user-independent zona pellucida imaging at the oocyte stage allows for the prediction of preimplantation development
Thomas Ebner, Ph.D.,et. al., Fertility and Sterility 2009, Austria
「卵母細胞の自動非使用者依存型透明帯画像診断は着床前発生の予測を可能にする - Birefringence characteristics in sperm heads allow for the selection of reacted spermatozoa for intracytoplasmic sperm injection
Luca Gianaroli, M.D. et al Italy
FERTIRRITY AND STERILITY VOL.93, NO.3, February 2010
精子頭部の複屈折性の特徴から先体反応精子の選別が可能である - Sperm DNA fragmentation ：mechanismes of origin, impact on reproductive outcome, and analysisDenny Sakkas, Ph.D. et al Massachusetts
FERTIRRITY AND STERILITY VOL.93, NO.4, March 2010
精子DNA断片化：発生のメカニズム、生殖への影響と分析 - Beneficicial effect of autologous endometrial cell coculture in patients with repeat implantation failure.
「反復不成功における自家内膜細胞との共培養の試み」 - Effect of vitrification and beta-mercaptoethanol on reactive oxygen species activity and in vitro development of oocytes vitrified before or after in vitro fertilization.
「ガラス化とβ-メルカプトエタノールが体外受精前後にガラス化した卵の活性酸素量と体外発生に与える影響」 - DNA fragmentation of normal spermatozoa negatively impacts embryo quality and intracytoplasmic sperm injection outcome.
「正常形態精子のDNA断片化が胚の質とICSIの影響に負の影響を与える」 - Analysis of spindle characteristics and embryo quality in mice stimulated with letrozole using Polscope image.
「レトロゾールの使用によるマウス卵子の紡錘体の特徴と胚のクオリティの検討」 - Impact of oocyte cryopreservation on embryo development.
「卵子凍結保存による胚発生への影響」 - Thyroid hormone supplementation improves bovine embryo development in vitro.
「甲状腺ホルモン添加はウシ胚の体外発生を改善する」 - Embryo quality and implantation rate in two different culture media: ISM1 versus Universal IVF Medium
「培地による胚の質と着床率の検討(ISM1 vs Universal IVF Medium)」 - Morphologic indicators predict the stage of chromatin condensation of human germinal vesicle oocytes recovered from stimulated cycles
形態学的指標は卵巣刺激周期で得られたヒト卵核胞期卵のクロマチン凝縮期を予測できる - Embryo development of fresh versus vitrified metaphase Ⅱ oocytes after ICSI : a prospective randamized sibling oocyte study
「ICSI後の胚発生－新鮮MⅡ卵子とガラス化MⅡ卵子について：余剰卵子を用いた前方視的無作為研究」 - A prospective, randomized trial on the effect of atmospheric versus reduced oxygen concentration on the outcome of intracytoplasmic sperm injection cycles
ICSIサイクルにおける大気 vs 低酸素の影響～前方視的無作為化試験～ - Does severe teratozoospermia affect blastocyst formation, live birth rate and other clinical outcome parameters in ICSI cycles?
B.et al. Fertil Steril.2010 USA
重度の奇形精子症はICSI周期の胚盤胞形成、出産率、その他の臨床結果に影響するか？ - Effect of air quality on assisted human reproduction
Human Reproduction 2010 USA
「ヒト生殖医療における大気質の影響」 - Comparison of 5% and ambient oxygen during days 3-5 of in vitro culture of human embryos
「Day3-5間での異なる酸素分圧による体外培養の比較（5% vs 外気酸素分圧）」 - Noninvasive metabolomic profiling as an adjunct to morphology for noninvasive embryo assessment in women undergoing single embryo transfer.
「単一胚移植おける非侵襲的な胚評価のための形態学の補助的な代謝分析」 - A new culuture technique that allows in vitro meiotic prophase development of fetal human oocytes.
Human Reprocuction,Vol.25,No.1pp.74-84 2010 Spain
「新しい培養技術は胎児ヒト卵子の体外での減数分裂期発生を可能にした」 - Clinical significance of sperm DNA damage in assisted reproduction outcome.
Human Reprocuction,Vol.25,No.7pp.1594-16088 2010 UK
「生殖医療における精子DNAダメージの臨床的重要性」 - Injection of day 2 embryo culture supernatant into the uterine cavity did not improve the pregnancy rate of day 3 embryo transfer in patients who underwent in vitro fertilization-embryo transfer: a randomized clinical trial
Fertil Steril. 2010 May 1;93(7):2216-21. Epub 2009 May 12.
「子宮腔内にday2胚培養液の上清を注入しても、day3でIVF-ETする患者の妊娠率は改善されない」 - Fall in implantation rates following ICSI with sperm with high DNA fragmentation
B.E.Speyer Human Reproduction 2010 UK
DNAフラグメンテーションが多い精子での着床率の低下 - Effect of gonadotropins on oocyte maturation in vitro : an animal model
Fertility and sterility Vol.93, No.5, March 15,2010 New York
「体外での卵子成熟におけるゴナドトロピンの効果：アニマルモデル」 - Evaluation of the immature human oocytes fro unstimulated cycles in polycystic ovary syndrome patients using a novel scoring system
Fertility and sterility Vol.93, No.7, May 1,2010 New York
「無刺激でのPCOS患者におけるIVM卵子の成熟度評価に対する新しいスコアリングシステムについて」 - Dynamic microfunnel culture enhancecs mouse embryo development and pregnancy rates
Y.S.Heo Human Reproduction 2010 USA
「動的マイクロ漏斗培養はマウス胚発育と妊娠率を高める」 - Primate model of metaphase I oocyte in vitro maturation and the effects of a novel glutathione donor on maturation, fertilization, and blastocyst development
C Eliza Fertility and Sterility,Vol.95,No.4,March 15,2011 Australia
「体内成熟卵子の霊長類モデルと成熟、受精、胚盤胞の発生における新しいグルタチオン供給の影響」 - Selection of viable spermatozoa from testicular biopsies: a comparative study between pentoxifylline and hypoosmotic swelling test
M Vijay Fertility and Sterility Vol.95, No.2, February 2011 India
「精巣生検による生存精子の選択：ペントキシフィリンと精子膨化テストの比較研究」 - Influence of embryo transfer on blastocyst viability
Grygoruk C et al., Fertil Steril. 2011 Mar 15;95(4):1458-61. Epub 2010 Jun 12.,Poland
胚移植が胚盤胞の生存性に与える影響 - In vitro maturation (IVM) of murine and human germinal vesicle (GV)-stage oocytes by coculture with immortalized human fallopian tube epithelial cells
HJ et al., Fertil Steril. 2011 Mar 15;95(4):1344-8. USA 不死化ヒト卵管上皮細胞と共培養したマウスおよびヒトGV卵の体外成熟
- Efficancy of oocyte vitrification combined with blastocyst stage taransfer in an egg donation program
Human reproduction, vol.26, No.4 pp.782-790, 2011, Peru
ドナー卵子における凍結胚盤胞移植の効果について - Aoutomatic user-independent zona pellucida imaging at the oocyte stage allows for the prediction of preimplantation development
「ユーザーに依存しない自動卵子透明帯イメージングは着床前発生の指標となる」 - Ultrastructual evaluation of human metaphaseⅡ oocytes after vitrification:closed versus open devices
ガラス化後のMⅡ卵子の超微細構造の評価：開放系デバイスVS閉鎖系デバイス - Vitrification of human ovarian tissue：effect of different solutions and procedures
Fertility and Sterility 2011 Belgium
「ヒト卵巣組織のガラス化：異なるガラス化溶液と手順の影響」 - Oocyte maturation failure：a syndrome of bad eggs
Fertility and Sterility 2011 Maryland (USA)
「卵母細胞成熟の失敗：不良卵症候群」 - In vitro maturation of human germinal vesicle-stage oocytes：role of epidermal growth factor-like growth factors in the culture medium
Human Reproduction 2011 Israel
「ヒトGV卵子成熟におけるIVM培地への上皮細胞増殖因子(EGF)like growth factor 添加の役割」 - Successful treatment of unresponsive thin endometrium
「子宮内膜が極めて薄い場合にホルモン剤の増量や血流改善薬以外の方法はあるか？」 - Influence of embryo sex on development to the blastocyst stage and euploidy
Fertility and Sterility 2011 Massachusetts
「胚盤胞ステージへの発育における胚の性と正倍数体の影響」 - Effect of embryo density and microdrop volume on the blastocyst development of mouse two-cell embryos
Fertility and Sterility 2011 Thailand
「マウス2cell胚の胚盤胞発育における胚の密度とドロップ量の影響」 - Role of semen analysis in subfertile couples
Fertility and Sterility 2011 Netherland
「低妊孕カップルにおける精子分析の役割」 - Morphological nucler integrity of sperm cells is associated with preimplantation genetic aneuploidy screening cycle outcomes
Fertility and Sterility 2011 Brazil
「精子細胞の形態学的核の無欠陥は着床前遺伝子診断異常検査と関連している」 - Dose cessation of progesterone supplementation durring early pregnancy in patients treated with recFSH/GnRH antagonist affect ongoing pregnancy rates? A randomized controlled trial
「アンタゴニストサイクルでの妊娠判明後、黄体ホルモン(P)補充は必要か？」 - Comparative analysis of tha metaphase Ⅱ spindle of human oocytes through polarized light and high performnce confocal microscopy
Fertility and Sterility 2010 Italy
「ヒトMⅡ期卵子のスピンドルを偏光顕微鏡と高性能共焦点顕微鏡を用いて観察した時の比較」 - Comprehensive chromosome screening of polar bodies and blastocysts from couples experiencing repeated implantation failure
Fertility & Sterility Vol. 94, No. 3, August 2010, New Jersey
反復不成功例における極体と割球の包括的染色体スクリーニング - Treating women under 36 years old without top-quality embryos on day 2: a prospective study comparing double embryo transfer with single blastocyst transfer
(Day 2 にTQEの無い35歳以下の女性の治療：2個の胚移植と1個の胚盤胞移植の比較) - Zona pellucida-induced acrosome reaction in human spermatozoa is potentiated by glycodelin-A via down-regulation of extracellular signal-regulated kinases and up-regulation of zona pellucida-induced calcium influx
「ヒト精子においてグリコデリン-A（GdA）による細胞外シグナル抑制キナーゼ（ERK）のダウンレギュレーションと透明帯のカルシウム流入のアップレギュレーションが透明帯の先体反応の誘導を促進する」 - Aberrant spindle structures responsible for recurrent human metaphase Ⅰoocyte arrest with attempts to induce meiosis artificially
ヒトMⅠ卵子の人為的減数分裂が阻まれる原因は紡錘体構造の異常にある - Prediction of pregnancy rate by blastocyst morphological score and age, based on 1,488 single frozen-thawed blastocyst transfer cycles
「胚盤胞の形態スコアと年齢による妊娠率の指標：1488の凍結融解単一胚移植サイクルより」 - Differential pH in embryo culuture
「胚培養におけるpHの差」 - The effectiveness of intracytoplasmic sperm injection combined with piezoelectric stimulation in infertile couples with total fertilization failure
完全受精障害の不妊カップルにおいて、圧電気刺激を組み合わせたICSIの効果 - Duration of progesterone-in-oil support after in vitro fertilization and embryo transfer: a randomized, controlled trial
IVF、ET後のプロゲステロン補充期間 無作為管理下試験 - The effect of modified quarter later-assisted zona thinning on the implantation rate per embryo in frozen/vitrified-thawed/warmed embryo transfer cycles：a prospective randomized controlled trial
「改良した1/4thinning法によるAHAの凍結融解胚に対する移植後の臨床成績について」 - Pregnancy outcomes in 188 French cases of prenatally diagnosed Klinefelter syndrome
「クラインフェルター症候群と出産前に診断されたフランス人188人の妊娠結果」 - The use of morphokinetics as a predictor of embryo implantation
「胚の形態の動的解析と着床率について」 - Human meiotic progression and recombination are affected by Bisphenol A exposure during in vitro human oocyte development
「体外培養したヒト卵子における減数分裂の進行及び組み換えはビスフェノールAの影響を受ける」 - In vitro development of secondary follicles from cryopreserved rhesus macaque ovarian tissue after slow-rate freeze or vitrification
「緩慢凍結もしくはガラス化凍結したアカゲザル卵巣組織由来の二次卵胞の体外発育」 - Microarray assessment of methylation in individual mouse blastocyst stage embryos shows that in vitro culture may have widespread genomic effects
「マウス胚盤胞でのメチル化のマイクロアレイ分析から体外培養はゲノムへの広範な影響を与えるかもしれないことが示された」 - Ultrastructure and intracellular calucium response during activation in vitrified and slow-frozen human oocytes
「ヒト卵子のガラス化凍結および緩慢凍結における活性化中の超微構造と内細胞のカルシウム反応」 - Aｎalysis of global gene expression following mouse blaM.G.Larman 2011 Human Reproduction stocyst cryopreservation
マウス胚盤胞の凍結保存後の遺伝子発現の分析 - Factors predicting the cumulative outcome of IVF/ICSI treatments: a multivariable analysis of 2450 patients
IVF/ICSI治療における累積結果の予測因子：患者2450人の多変数分析 - Implications of blood type for ovarian reserve
血液型と卵巣保有能との関係 - MicroRNAs are associated with human embryo implantation defect
「MicroRNAは着床不全に関与する」 - Trophectoderm morphology: an important parameter for predicting live birth after single blastocyst transfer
TEの形態は単一胚盤胞移植後の出産を予測する重要なパラメーターである - Clinical outcomes and development of children born after intracytoplasmic sperm injection (ICSI) using extracted testicular sperm or ejaculated extreme severe oligo-astheno-teratozoospermia sperm：a comparactive atudy
「精巣精子と射出された重度の乏精子―無力精子―奇形精子(OAT)を用いたICSI後の臨床成績と生まれた子供の発育について：比較研究」 - comparison of in vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal crod injuries
「脊髄損傷がある男性不妊患者と他の男性因子不妊患者におけるIVF/ICSI結果の比較」 - The competence of germinal vesicle oocytes is unre;ated to nuclear chromatin configuration and strictly depends on cytoplasmic quantity and quality in the cat model
GV卵子の能力は核クロマチンの配置に関係せず、細胞質の質や量に依存している。 - Implications of blood type for ovarian reserve
血液型と卵巣保有能との関係 - MicroRNAs are associated with human embryo implantation defects
「MicroRNAは着床不全に関与する」 - Glucose consumption of single post-compaction human embryos is predictive of embryo sex and live birth outcome.
桑実胚以降のヒト胚のグルコース消費量は胚の性別と出生余予後を予測する - A pragmatic RCT of conventional versus increased concentration sucrose in freezing and thawing solutions for human embryos.
ヒト胚に対する凍結融解液へのsucroseの通常濃度添加 対 強化濃度添加の実践的RCT - Comparison of Cryotip vs. Cryotop for mouse and human blastomere vitrification
Fertility and Sterility 2012
「マウスおよびヒト割球のガラス化凍結におけるCryotipとCryotopとの比較」 - Developmental potential of embryos from intracytoplasmic sperm injection cycles containing fragmented oocytes.
フラグ化卵子を含むICSI周期での胚の発生能 - Selection of high-potential embryos by culture in poly (dimethylsiloxane) microwells and time-lapse imaging
ポリマイクロウェルでの培養とタイムラプス像による優良胚の選択 - Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen activators during interplay between gametes.
「卵管中のプラスミノーゲン活性因子放出は受精成立に影響を与える」 - Semen analysis:looking for an upgrade in class
「精子検査：クラスのアップグレードの探求」 - Phospholipase C-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection
「ホスホリパーゼCにより誘発されるCaオシュレーションはICSI後受精が成立しなかったヒト卵子の細胞質の変化と一致する」 - Nitric oxide synthase and tyrosine nitration in idiopathic asthenozoospermia: an immunohistochemical study
「特発性精子無力症における一酸化窒素シンターゼとチロシン・ニトロ化：免疫組織化学的研究」 - Superoxide dismutase content in sperm correlates with motility recovery after thawing of cryopreserved human spermatozoa
Mariano G.Buffone,Ph.D. Fertility and Sterility Vol.97,No.2 February 2012 America
「精子におけるスーパーオキシドジスムターゼ(SOD:超過酸化物不均化酵素)は凍結ヒト精子融解後の運動率回復と相関する」 - Human sperm head vacuoles are physiological structures formed during the sperm development and maturation process
Fertility & Sterility 2012 USA
「ヒト精子頭部の空胞は精子発生と成熟の過程の中で生理学的な構成を形作る」 - Effects of low molecular weight heparin and heparin-binding epidermal growth factor on human trophoblast in first trimester
Fertility & Sterility, Vol. 97, No. 3, 2012, China
低分子ヘパリンおよび、ヘパリン結合型上皮細胞増殖因子の妊娠初期におけるヒト栄養膜細胞への効果について - Is the zona pellucida thickness of human embryos influenced by women’s age and hormonal levels?
(ヒト胚の透明帯の厚さは女性の年齢とホルモン値に影響を受けるのか？) - Trophectoderm morphology significantly affects the rates of ongoing pregnancy and miscarriage in frozen-thawed single-blastocyst transfer cycle in vitro fertilization
Fertil Steril. 2012 Aug 98(2):
単一凍結融解胚盤胞移植周期におけるTEの形態は継続妊娠率及び流産率に影響する - The effect of GM-CSF on development and aneuploidy in murine blastocysts.
Human Reproduction,vol.27,No.6 pp.1590-1595,2012 UK
マウスの胚盤胞での異数性と発生におけるGM-CSFの影響 - 「Day3 embryo selection by metabolomic profiling of culture medium with near-infrared spectroscopy as an adjunct to morphology: a randomized controlled trial.」
Human Reproduction, Vol27, No8pp.2304-2311, 2012 USA
近赤外分光法による培地の代謝産物の分析とDay3胚の選択 - 「Sperm DNA fragmentation index does not correlate with the sperm or embryo aneuploidy rate in recurrent miscarriage or implantation failure patients」
Human Rproduction, Vol27, No7pp. 1992-1929, 2012 Spain
精子DNA断片化指数は再発する流産または胚移植失敗患者で精子または胚の異数性率と相関しない - Full in vitro fertilization laboratory mechanization: toward robotic assisted reproduction?
Fertility & Sterility, Vol. 97, No. 6, 2012, Denmark
体外受精ラボは完全機械化、ロボット化できるのか？ - Age-associated alterration of oocyte-specific gene expression in polar bodies：potential markers of oocyte competence
Fertility & Sterility, Vol. 98, No. 2, 2012, Cicago
卵子特有の極体の遺伝子発現は年齢とともに変化する：卵子能の指標となる可能性について - Assisted oocyte activatoin is not beneficial for all patients with a suspected oocyte-related activation deficiency
Human Reproduction, Vol.27, No.7, pp.1977-1984 2012 Belgium
「卵活性化補助はすべての卵活性化不良の患者にとって有利とはいえない」 - Effects of combined epidermal growth factor, brain-derived neurotrophic factor and insulin-like growth factor-1 on human oocyte maturation and early fertilized and cloned embryo development
EGF,BDNF,IGF-1がヒト卵子の成熟、受精卵及びクローン胚の早期胚発生に与える影響」 - Heparin enhances protamine disulfide bond reduction during in vitro decondensation of human spermatozoa
ヘパリンは体外におけるヒト精子の脱凝縮の間にジスルフィド結合の還元を高める - Difference in transcriptomic profiles of fuman cumulus cells isolated from oocytes at GV、MⅠ、MⅡ stage after in vivo and in vitro oocyte maturation
体内または体外卵子成熟過程で得られたGV、MⅠ、MⅡの卵丘細胞の転写分析 - Further evidence that culture media affect perinatal outcome：findings after transfer of fresh and cryopreserved embryos
体外培養に使用する培養液によって分娩結果は影響を受ける - Exposure to lipid-rich follicular fluid is associated with endoplasmic reticulum stress and impaired oocyte maturation in cumulus-oocyte complexes
Fertility and Sterility 2012.Australia
脂質の高い卵胞液への暴露は細胞質の網状質を圧迫し、卵丘細胞卵子複合体において卵子の成熟が阻害される - Outcomes of vitrified early cleavage-stage and blastocyst embryos in a cryopreservation program: evaluation of 3,150 warming cycles
Fertility and Sterility 2012.Spain
ガラス化した初期分割胚と胚盤胞の凍結プログラムにおける結果：3,150の融解サイクルの評価 - The value of chromosomal analysis in oligozoospermic men
Fertility and Sterility 2012. Netherlands
乏精子症男性における染色体評価の価値 - Sperm vacuoles are linked to capacitation and acrosomal status.
Human Reproduction Vol.27,No.10 pp.2927-2932,2012 France
精子空胞はキャパシテーションと先体の状態に関係する - BMI-related metabolic composition of the follicular fluid of women undergoing assisted reproductive treatment and the consequences for oocyte and embryo quality
ART周期の女性の卵胞液の代謝組成とBMIの関連及び卵子・胚に与える影響 - Preimplantation genetic diagnosis: a systematic review of litigation in the face new technology
着床前遺伝子診断：新規技術に直面しての法的紛争のシステマティックレビュー - Successful delivery derived from vitrified-warmed spermatozoa from a patient with nonobstructive azoospermia
非閉塞的無精子症患者のガラス化凍結融解した精子から出産に成功した - Limited implantation success of direct-cleaved human zygotes：a time-lapse study
Fertility and Sterility 2012 Denmark
「着床成功率と受精直後の分割との関係」（ﾀｲﾑﾗﾌﾟｽを用いた検討） - Application of a ready-to-use calcium ionophore increases rates of fertilization and pregnancy in severe male factor infertility
Fertility and Sterility 2012 Germanyk
「既製のカルシウムイオノフォア使用によって重度の男性因子不妊患者において受精率および妊娠率が増加する」 - The effect of maternal age on chromosomal anomaly rate and spectrum in recurrent miscarriage
Fertility and Sterility 2012 Germanyk
「母体年齢が染色体異常率と反復流産に与える影響」 - Motile sperm organelle morphology evaluation-selected globozoospermic human sperm with an acrosomal bud exhibits novel patterns and higher levels of phospholipase C zeta
「運動精子細胞小器官形態評価選別された先体芽を持つ巨大頭部精子症のヒト精子はホスホリパーゼCゼータの新しいパターンと高いレベルを示す」 - Altered gene expression profile in cumulus cells mature M2 oocytes from patients with polycystic ovary syndrome
Human Reproduction France
「PCO患者から得られた成熟卵丘細胞の変化した遺伝子発現状況について」 - Follicle microenvironment-associated alterations in gene expression in the mouse oocyte and its polar body
Fertility and Sterility U.S.A
「卵胞内環境とマウス卵子、極体の遺伝子発現との関係について」 - Blastocyst preimplantation genetic diagnosis(PGD) of a mitochondrial DNA disorder
Fertility and Sterility New York
「胚盤胞を使ったミトコンドリアDNA異常の着床前遺伝子診断」 - Trophectoderm grade predicts outcome of single-blastocyst transfers Fertility and Sterility Maryland
Fertility and Sterility 2013 Denmark
「栄養外胚葉のグレードは単一胚盤胞移植の結果を予測する。」 - Effect of oxygen concentration on human embryo development evaluated by time-lapse monitoring
Fertility and Sterility 2013 Denmark
タイムラプスモニタリングによるヒトの胚発生評価における酸素濃度の影響 - In vitro development and chromosome constitution of embryos derived from monopronucleated zygotes after intracytoplasmic sperm injection.
Fertility and Sterility,Vol.99,No.3,March,2013 Spain
ICSI施行後1PNが見られた胚の染色体構造と体外発生 - Impact of follicular G-CSF quantification on subsequent embryo transfer decisions ： a proof of concept study
Human Reproduction Belgium
「胚移植選択における卵胞G-CSF量の影響：概念研究の立証」 - Biomarkers identified with time-lapse imaging : discovery, validation, and practical application
Fertility and Sterility USA
「タイムラプス画像によって識別されるバイオマーカーについて」 - Embryo whose polar bodies contain isolated reciprocal chrosome aneuploidy are almost always euploid
「相互に分離した異数性を含む極体を持つ胚の大部分は正倍数体である。」 - Intracytoplasmic morphologically selected sperm injection versus intracytoplasmic sperm
injection:astep toward a clinical algorithm
IMSI vs ICSI：アルゴリズムに向けての段階 - Use of hyaluronan in the selection of sperm for intracytoplasmic sperm injection (ICSI): significant improvement in clinical outcomes-multicenter, double-blinded and randomized controlled trial
「ICSIの精子選択時に用いたヒアルロン酸による臨床成績の上昇」 - Effect of ICSI on gene expression and development of mouse preimplantation embryos
「ICSI後のマウス胚の発生と遺伝子発現について」 - Optimaizing human oocyte cryopreservation for fertility preservation patients：sould we mature then freeze or freeze then mature?
Fertility and Sterility New York 2013
「未熟卵子の凍結は成熟後にするべきか成熟前にするべきか？」 - Is the nuclear status of embryo an independent factor to predict its ability to develop to them?
Fertility and Sterility France 2013
「胚の核の状態は次期発達予測の独立した要因となるか」 - 「Semi-automated morphometric analysis of human embryos can reveal correlations between total embryo volume and clinical pregnancy
ヒト胚形態評価の半自動化は胚の容量と臨床的な妊娠の相関関係を明らかにする。 - Human trophectoderm cells are not yet committed
ヒトTE細胞はまだ発生方向が決定されていない - Analysis if metabolism to select viable human embryos for transfer
胚移植の為のヒト胚の選択における代謝分析 - Fresh embryo transfer versus frozen embryo transfer in in vitro fertilization cycles:a systematic review and meta-analysis
システマティックレビューとメタアナリシスによる新鮮胚移植と凍結融解胚移植の比較 - Cryoprotectants up-regulate expression of mouse oocyte AQP7、which facilitates water diffusion during cryopreservation
Fertility and Sterility 2013 China
「マウス卵子のAQP7により凍結保存における水の拡散が促進され凍結保護剤の調節機能が上がる」 - Evaluation of an sffective multifaceted implementation strategy for elective single embryo transfer after in vitro fertilization
Human Reproduction 2013 Netherlan
「IVF後の選択的単一胚移植のための有効な多面的実現戦略の評価」 - Sequential comprehensive chromosome analysis on polar bodies, blastomeres and trophoblast: insights into female meiotic errors and chromosomal segregation in the preimplantation window of embryo development
Human Reproduction, 2013, Italy
極体、割球およびトロフェクトダームの連続包括的染色体分析：胚発生過程での女性側の減数分裂不良または染色体分離不良に焦点をおいた研究 - Vitrification preserves proliferstion capacity in human spermatogonia
「ガラス化はヒト精原細胞の増殖能力を維持する」 - Diagnostic and prognostic value of calcium oscillatory pattern analysis for patients with ICSI fertilization failure
「ICSI受精障害患者のCa2+増加パターンによる診断と予測値について」 - Novel technologies for selecting the best sperm for in vitro fertilization and intracytoplasmic sperm injection
Fertility and Sterility 2013 US
体外受精とICSIのための最良精子選別の新技術 - Perfringolysin O as a useful tool to study human sperm physiology
Fertility and Sterility 2013 US
ヒト精子生理機能研究の有用ツールとしてのパーフリンゴリジン - Preimplantation genetic screening using fluorescence in situ hybridization in patients with repetitive implantation failure and advanced maternal age: two randomized trials
C Rubio et al, Fertil Steril. 2013 Apr;99(5):1401-07. ,Spain
FISH法を用いた着床不全および高齢女性の着床前診断 - Preimplantation human blastocysts release factors that differentially alter human endometrial epithelial cell adhesion and gene expression relative to IVF success
Human Reproduction, Vol. 28, No. 5, 2013, Australia
ヒト胚盤胞が放出する子宮内膜上皮細胞の接着と遺伝子発現を変化させる因子についてHuman Reproduction, Vol. 28, No. 5, 2013, Australia - FISH reanalysis of inner cell mass and trophectoderm samples of previously array-CGH screened blastocysts shows high accuracy of diagnosis and no major diagnostic impact of mosaicism at the blastocyst stage.
Human Reproduction, Vol.28, No.8 2013 USA
CGH法に加えてFISH法で胚盤胞のICMとTEの染色体分析をすることにより、より正確なモザイク胚の診断が可能となる - Dose intracytoplasmic morphologically selected sperm injection improve embryo development?A randomized sibling-oocyte study
Human reproduction 2013.Belgium
「細胞質内を形態学的に選別した精子の注入により胚発育は改善するか。余剰卵子を使った無作為研究」 - Sperm vacuoles negatively affect outcomes in intracytoplasmic morphologically selected sperm injection in terms of pregnancy,implantation,and live-birth rates
Fertility and Sterility Vol 100 2013
「精子空胞はIMSI転帰(妊娠率・着床率・出生率)に悪影響を及ぼす」 - Evolution of aneuploidy up to Day 4 of human preimplantation development
Human reproduction 2013.Belgium
「着床前のヒトDay4胚発生までの異数性の進化」 - Polar body analysis by comparative genomic hybridization accurately predicts aneuploidies of maternal meiotic origin in cleavage stage embryos of woman of advanced maternal age
Human reproduction 2013 UK
「アレイCGH(比較ゲノムハイブリダイゼーション)による極体の分析は、高齢女性の分割ステージ胚における減数分裂起源の異数体を正確に予想する」 - Lower intracellular concentration of cryoprotectants after vitrification than after slow freeging despite exposure to higher concentration of cryoprotectant solutions
Human reproduction 2013
「高濃度の耐凍剤溶液を使用しているにも関わらず、ガラス化凍結後の胚は緩慢凍結法よりも細胞内耐凍剤濃度が低い」 - What is the best cryopreservation protocol for human testicular tissue banking?
Human reproduction 2013 Belgium
「ヒト精巣組織バンクにおいて一番良い凍結保存方法は何か？」
